Protein Alignment alpha-Est2 and ache

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 602
• Identity: 166/602 - (27%)
• Similarity: 271/602 - (45%)
• Gaps: 113/602 - (18%)

  Fly    33 VILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCT------- 90
            :::.|:.|:|:| .|..|.|:....||.|||||:||:|..||:..:|.:||..|....
Zfish    29 LVVATRLGRVQG-TRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACY 92

  Fly    91 --TNRSKP-------MQRNMLLGIVEGSEDCLHLNVYVKALKSEKPLPVIVWIYGGGFQKGEASR 146
              .:.|.|       ...|.::     |||||:|||:|......:.|.|:||||||||..|.:|.
Zfish    93 QFVDTSYPGFPGIEMWNPNRVM-----SEDCLYLNVWVPPTPRPQNLTVMVWIYGGGFYSGSSSL 152

  Fly   147 DIYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDP 210
            |:|...|. ..:.||.|::|||:.|.|||:|.... |.|||.||.||.:||:|:.:||..|.|:|
Zfish   153 DVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSS-DAPGNVGLYDQRLALQWVQENIHFFGGNP 216

  Fly   211 NNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWA-----------FRL 264
            ..:|:.|||||:|||.:.:.:..:|.||.:||:|||.        |:..||           .:|
Zfish   217 KQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGV--------PNTPWATVTFDEARRRTTKL 273

  Fly   265 AQNLGYKGDEKDADVLSFLSKVCARQIAAIDQD--VINLDEVRSFLLFAFGPVIEPYETDHCVVP 327
            .:.:|.... .|.:::..|.....:::  |||:  |:...   |...|:|.||:     |....|
Zfish   274 GKLVGCTWG-NDTELIDCLRNKHPQEL--IDQEWQVLPWS---SLFRFSFVPVV-----DGVFFP 327

  Fly   328 KRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPRE---------VRETSS 383
            .....::|........:::|.|..||  ||.|:...|...|:..:::.||         |...:.
Zfish   328 DTPDAMISSGNFKYTQILLGVNQDEG--SYFLLYGAPGFSKDNESLISREDFLESVKMGVPHAND 390

  Fly   384 LEGQDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSY----------APK 438
            : |.:.::.:.......|..|::.:..:  :|...:.:......|..:...|          ||.
Zfish   391 I-GLEAVILQYTDWMDENNGQKNRDAMD--DIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPG 452

  Fly   439 T-------PT-----------YLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLFYNIIASK 485
            |       ||           |||.||..:.:       :......||.|..|:.::|...:..:
Zfish   453 TLGWGNSGPTGYNSGNSHGAVYLYLFDHRASN-------LAWPEWMGVIHGYEIEFVFGLPLEKR 510

  Fly   486 LDKSSMEYKTIERMVGMWTSFASSGNPNCPELGS----AKWEAVQLKENAVEKCFNISHD-LEMR 545
            |:.::.|.|...|::..|.:||.:||||....|:    .:|......|   :|...::.: :::.
Zfish   511 LNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQFSANE---QKHVGLNTEPMKVH 572

  Fly   546 DLPESDCLAVWDTFYPR 562
            ....:...|:|:.|.||
Zfish   573 KGLRTQFCALWNRFLPR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	158/560 (28%)
		Aes	<117..>221	CDD:223730	48/104 (46%)
ache	NP_571921.1	COesterase	23..583	CDD:278561	162/594 (27%)
		AChE_tetra	598..631	CDD:285837

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740