DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-Est2 and LOC107987423

DIOPT Version :9

Sequence 1:	NP_001262345.1	Gene:	alpha-Est2 / 40908	FlyBaseID:	FBgn0015570	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	278	Identity:	63/278 - (22%)
Similarity:	111/278 - (39%)	Gaps:	66/278 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 GPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFE-------GLFSY-----QLVRKDPW 365
            |.||     |..::.|..::|.:|...:.:|.:||.|..|       .|.||     ||.:|...
Human    39 GTVI-----DGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAM 98

  Fly   366 AL--KNF------HNILPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFEALNIFSHRQIW 422
            :|  |::      ..::|....:  .|.|.|..|:: |.|:              |::.:  .:.
Human    99 SLLWKSYPLVCIAKELIPEATEK--YLGGTDDTVKK-KDLF--------------LDLIA--DVM 144

  Fly   423 HDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFR--RLVCGDRIRGVAHADELSYLFYNIIAS- 484
            ......|:||.......|||:|.|.: .|.|:...  :.|.||      |.|||    :::..:
Human   145 FGVPSVIVARNHRDAGAPTYMYEFQY-RPSFSSDMKPKTVIGD------HGDEL----FSVFGAP 198

  Fly   485 --KLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEMRDL 547
              |...|..|.:..:.::..|.:||.:||||..  |...|.....||..::...|.....:::|.
Human   199 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGE--GLPHWPEYNQKEGYLQIGANTQAAQKLKDK 261

  Fly   548 PESDCLAVWDTFYPRESL 565
            .    :|.|...:.::::
Human   262 E----VAFWTNLFAKKAV 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	56/234 (24%)
alpha-Est2	NP_001262345.1	Aes	<117..>221	CDD:223730
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010