Protein Alignment alpha-Est2 and Ces2

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 180/567 - (31%)
• Similarity: 258/567 - (45%)
• Gaps: 94/567 - (16%)

  Fly     7 WPKLIKMGAQLVGHKVQ------QYRLSTGHTVILDTKYGQVRGLQRKTVYDKEPYFAFEGIPYA 65
            |...:..|..|:...||      ...:.|.||       |||:|........|.....|.|||:|
  Rat     9 WLNAVLFGLLLLLIHVQGQDSPESSPIRTTHT-------GQVQGKLDHVKDTKAGVHTFLGIPFA 66

  Fly    66 KPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQR------------NMLLGIVEGSEDCLHLNVY 118
            |||||.|||..|:|||||.||.:.|:..:..:|.            .|:|..:..|||||:||||
  Rat    67 KPPVGPLRFAPPEPPEPWSGVRDATSQPAMCLQNLDILDEVGLLDMKMILSSISMSEDCLYLNVY 131

  Fly   119 VKALKSE-KPLPVIVWIYGGGFQKGEASRDIYSPDYF-MKKPVVFVAINYRLAALGFLSLKDPKL 181
            ..|...| ..|||:|||:||....|.||  :|..... :.:.:|.|.|.|||..|||.|..|.
  Rat   132 APAHAREGSNLPVMVWIHGGALVVGMAS--MYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDE-- 192

  Fly   182 DVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSG 246
            ...||.|..|||.||||:.||||||.|:||.:|:.|||||..||...:.:..::||||.|||:||
  Rat   193 HARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESG 257

  Fly   247 CA-LSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLDEVRSFLLF 310
            .| |.:.:.......:..:|:..|.:..:.:|.|.      |.|..:..:..|||       .:|
  Rat   258 VALLPDLISETSETVSTTVAKLSGCEAMDSEALVR------CLRAKSGAEILVIN-------KVF 309

  Fly   311 AFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILP 375
            ...|.:    .|...:|:..|:||:....:.:|.|:|.|:.|...:..:|......:|.    |.
  Rat   310 KMIPAV----VDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKE----LS 366

  Fly   376 RE-----VRETSSL-----EGQDLLVRRLKQLYFNN-------EMQESMEMFEALNIFSHRQIWH 423
            ||     :::|::.     |..|||:..    |..|       ::|.:..|.:.|.:....|:.|
  Rat   367 RENLQAVLKDTAAQMMLPPECGDLLMEE----YMGNTDDSQTLQIQYTEMMGDFLFVIPALQVAH 427

  Fly   424 DTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFR-RLVCGDRIRGVAHADELSYLFYNIIAS-KL 486
                   .::|:|   |.|.|.|.....:|...| ..|..|      ||||:.::|.:..:. ||
  Rat   428 -------FQRSHA---PVYFYEFQHAPSYFKNVRPPHVKAD------HADEVPFVFGSFFSGMKL 476

  Fly   487 DKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVE 533
            |.:..|.....||:..|.:||..||||..  |...|.|:...|..::
  Rat   477 DFTEEERLLSRRMMKYWANFARQGNPNSE--GLPYWPALDHDEQYLQ 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	172/534 (32%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	175/544 (32%)