Protein Alignment alpha-Est2 and nlgn3

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 180/663 - (27%)
• Similarity: 276/663 - (41%)
• Gaps: 183/663 - (27%)

  Fly    18 VGHKVQQYRLS-------------TGHTVI----LDTKYGQVRGLQRKTVYDKE---PYFAFEGI 62
            ||.||...:||             :.|..:    ::|.||::||  .:.....|   |...:.|:
 Frog     4 VGLKVAPRKLSLVLWVLSVTSRVLSSHAQVYSQTVNTHYGKLRG--TRVPLPSEILGPVDQYLGV 66

  Fly    63 PYAKPPVGDLRFRAPQPPEPWQGVLN-------CTTNRSKPMQRNML-------LGIVEG----- 108
            |||.||||:.||..|:||..|.|:.|       |..|....:...|:       |..|.|
 Frog    67 PYAAPPVGEKRFLPPEPPPSWSGIRNATHFSPVCPQNIQNAVPDIMMPVWFTSNLDTVTGYLQEQ 131

  Fly   109 SEDCLHLNVY-----VKALKSE---KP-----------------------------------LPV 130
            |||||:||:|     ||.:..|   ||                                   .||
 Frog   132 SEDCLYLNIYVPTEDVKRISKECVRKPNKKICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPV 196

  Fly   131 IVWIYGGGFQKGEASRDIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMA 195
            :|:|:||.:.:|..:. |..........||.:.:|||:..|||||..|..  ..||.||.||:.|
 Frog   197 MVYIHGGSYMEGSGNM-IDGSVLASYGNVVVITLNYRVGVLGFLSTGDQA--AKGNYGLLDQIQA 258

  Fly   196 LRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEW-VESPDNN 259
            |||:|:|:|.|.|||:.||:.|...|::.|.::..:..:.|||.:||:|||.|||.| |......
 Frog   259 LRWVSENVAFFGGDPHRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVK 323

  Fly   260 WAFRLAQNLGYKGDEKDADVLSFLSKV-CARQIAA---IDQDVINLDEVRSFLLFAFGPVIEPYE 320
            :...||:.:|       .:||..:..| |.||.:|   ::||:   ...|..:  ||||||
 Frog   324 YTRLLAEKVG-------CNVLDTVDMVDCLRQKSAKELVEQDI---QPARYHV--AFGPVI---- 372

  Fly   321 TDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGL-FSYQLVRKD--------PWALKNFHNIL-- 374
             |..|:|...:.|:.:....:..:::|.|..||| |...:|..:        .:::.||.:.|
 Frog   373 -DGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVENVVDAEDGVSGSDFDYSVSNFVDNLYG 436

  Fly   375 -PREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMFE--ALNIFSHRQ------IWHDTHRFIL 430
             |         ||:|.|...:|.:|.:...:::.|...  .:.:|:..|      :..|.|
 Frog   437 YP---------EGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLH---- 488

  Fly   431 ARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYLF-------YNIIASKLDK 488
            ||..    :|||.|.|   ..|.....:....|    .||.||:.|:|       .::......|
 Frog   489 ARYG----SPTYFYAF---YHHCQSLMKPAWAD----AAHGDEVPYVFGVPMVGPTDLFPCNFSK 542

  Fly   489 SSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEMRDLPESDCL 553
            :.:....:  ::..||:||.:|:||.|.....|:  :..|.|..|:
 Frog   543 NDVMLSAV--VMTYWTNFAKTGDPNKPVPQDTKF--IHTKANRFEE------------------- 584

  Fly   554 AVWDTFYPRESLF 566
            ..|..:.||:.|:
 Frog   585 VAWSKYNPRDQLY 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	169/622 (27%)
nlgn3	XP_012823589.1	COesterase	35..618	CDD:395084	173/632 (27%)