Protein Alignment alpha-Est2 and nlgn1

DIOPT Version :10

• Sequence 1: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 679
• Identity: 176/679 - (25%)
• Similarity: 279/679 - (41%)
• Gaps: 183/679 - (26%)

  Fly     4 QVGWPKLIKMGAQ---------LVGH--KVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDKE--- 54
            :|.|.:.:.||..         .:.|  .|:..:|.....|:| |.||:|||.:::  .:.|
 Frog    14 RVTWLRFLPMGLDSTFVLCVFGFLLHIATVRSQKLDDVDPVVL-TTYGKVRGFKKE--LNNEILG 75

  Fly    55 PYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLLG--------------- 104
            |...|.|:|||.||:|:.||:.|:||..|..:.|.|  :..|:....::|
 Frog    76 PVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKNST--QFAPVCPQNIVGGRLPEVMLPVWFTNN 138

  Fly   105 -------IVEGSEDCLHLNVYV------------------KALKSEKPL---------------- 128
                   :.:.|||||:||:||                  |..:.|.||
 Frog   139 LDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKEGPLTKKQTDDLGDNEGAED 203

  Fly   129 ----------PVIVWIYGGGFQKGEASRDIYSPDYFMK-KPVVFVAINYRLAALGFLSLKDPKLD 182
                      ||:|:|:||.:.:|  :.:::....... ..|:.:.:||||..|||||..|..
 Frog   204 EDIRDSGGPKPVMVYIHGGSYMEG--TGNVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQA-- 264

  Fly   183 VPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMT---------TEQTRGLF 238
            ..||.||.|.:.||||.|:||..|.|||..||:.|..||::.|:::..         :..|:|||
 Frog   265 SKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLF 329

  Fly   239 HKAIMQSGCALSEW-VESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQIAAIDQDVINLD 302
            .:||.|||.|||.| |......:|..||..:|....: ..:::..|.|...|::  :|||:   .
 Frog   330 QRAIAQSGTALSSWAVSFQPAKYARILATKVGCNMSD-SGELVECLQKKPYREL--VDQDI---Q 388

  Fly   303 EVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEGL-FSYQLVRKD--- 363
            .||..:  ||||||     |..|:|...:.|:.:....:..:::|.|..||| |....|..:
 Frog   389 PVRYHI--AFGPVI-----DGDVIPDDPQVLMEQGEFLNYDIMLGVNQGEGLKFVESTVDHEDGV 446

  Fly   364 -----PWALKNFHNILPREVRETSSLEGQDLLVRRLKQLYF-----NNEMQESMEMFEALNIFSH 418
                 .:|:.||.:.|      ....||:|:|...:|.:|.     ||.......:   |.:|:.
 Frog   447 SSSDFDFAVSNFVDNL------YGYTEGKDILRETIKFMYTDWADRNNPETRRKTL---LALFTD 502

  Fly   419 RQIWHDTHRFILARQSYAPKTPTYLYRFDFDSP-HFNQFRRLVCGDRI---RGVAHADELSYLF- 478
            .| |            .||...|.....:|.|| :|..|......|::   ...:|.||:.|:|
 Frog   503 HQ-W------------VAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADASHGDEIPYVFG 554

  Fly   479 ------YNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFN 537
                  ..:......|:.:....:  ::..||:||.:|:||.|.....|:  :..|.|..|:
 Frog   555 IPMIGPTELFPCNFSKNDVMLSAV--VMTYWTNFAKTGDPNQPVPQDTKF--IHTKPNRFEE--- 612

  Fly   538 ISHDLEMRDLPESDCLAVWDTFYPRESLF 566
                            ..|..:..::.|:
 Frog   613 ----------------VAWTRYSQKDQLY 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	166/626 (27%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	169/641 (26%)