Protein Alignment alpha-Est2 and ces3.1

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces3.1 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 590
• Identity: 164/590 - (27%)
• Similarity: 243/590 - (41%)
• Gaps: 166/590 - (28%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKEP---YFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSK 95
            :|.|||||:.|   |||..||.   ...|.|:|:||||:|.|||.||||||||..|...|.....
 Frog    26 LLMTKYGQLLG---KTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSVREATAPSPM 87

  Fly    96 PMQRNMLLGIVEG-----------SEDCLHLNVYVKALKSEKP-LPVIVWIYGGGFQKGEASR-- 146
            .:|...::.::..           |||||:|||:..|.|.|.| |||:|:|:|||...|.||.
 Frog    88 CLQDKEVMELLADFFKAKFDFSRVSEDCLYLNVFTPADKGENPGLPVMVFIHGGGLAIGGASMFE 152

  Fly   147 ----DIYSPDYFMKKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFN 207
                ..|       :.||.|:|.|||..:||||..|.  :|.||.|..|||.||:|:..||..|.
 Frog   153 GSALSAY-------ENVVVVSIQYRLGIMGFLSTGDK--EVRGNFGFLDQVAALQWVRDNIKDFG 208

  Fly   208 GDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKG 272
            |||.::|:.|||||..||..::.:..:.||||:||.:||.|:...:.:
 Frog   209 GDPQSVTIFGESAGGLSVSALVLSPLSEGLFHRAIAESGVAILPGLTA----------------- 256

  Fly   273 DEKDADVLSFLSKV-------------CARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHC 324
             .|..::|..|..|             |.:.  ..:.::|.:.....:::|       |...|..
 Frog   257 -SKTEEILPLLDMVINVSSCSVSDLVGCLKN--KTEDEIIEITAAMRYVIF-------PAVVDGV 311

  Fly   325 VVPKRHKDLLSEAWGNDIPVIVGGNSFEGLFSYQLVRKDPWALKNFHNILPREVRETSSLEGQDL 389
            .:||..:::|:....:.:|.::|.|:.|                 |.::||..:..|...||.:
 Frog   312 FLPKPAEEILAAKESHPVPFLIGINNHE-----------------FGSMLPVTLNITGYREGME- 358

  Fly   390 LVRRLKQLYFNNEMQESMEMFEALNI------FSHRQIWHDTHR----------------FIL-- 430
                      ..::|..:.....||.      |...:.:.||:.                |::
 Frog   359 ----------KKDIQAILGALPLLNTVSSVIPFIMEEYFGDTNDPKELRNNFLDLAGDIIFVIPA 413

  Fly   431 ---ARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVA---HADELSYL-----FYNIIAS 484
               |:.......|.|.|.|        |.|..:..|......   |.|||.::     ..|.|..
 Frog   414 LRTAKYHRDSGFPVYFYEF--------QHRPSLYADSKEDFVKADHGDELYFVGGGPFLKNGILF 470

  Fly   485 K---------LDKSSMEYKTIERMVGMWTSFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISH 540
            |         |.|:.|:|         |.:||.:|:||  ..|.|:|......|:.:|  .|::.
 Frog   471 KSNGTEEEKILSKTIMKY---------WANFARNGDPN--GHGLAEWPKYDEDEDYLE--INLTQ 522

  Fly   541 DLEMR 545
            ....|
 Frog   523 KSSQR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	159/566 (28%)
		Aes	<117..>221	CDD:223730	49/110 (45%)
ces3.1	NP_001120019.1	COesterase	25..536	CDD:365897	164/590 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16997
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940