Protein Alignment alpha-Est2 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 647
• Identity: 166/647 - (25%)
• Similarity: 265/647 - (40%)
• Gaps: 189/647 - (29%)

  Fly    34 ILDTKYGQVRGLQRKTVYDKE---PYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSK 95
            |:.|.||:|||.:::  .:.|   |...|.|:|||.||.|:.||:.|:||..|..:.|.|  :..
Zfish    55 IVTTTYGKVRGFKKE--LNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNAT--QFA 115

  Fly    96 PMQRNMLLG----------------------IVEGSEDCLHLNVY-----VKALKSE-------- 125
            |:....||.                      :.:.|||||.||:|     ||.:..|
Zfish   116 PVCPQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKK 180

  Fly   126 -------------------------------KPLPVIVWIYGGGFQKGEASRDIYSPDYFMK-KP 158
                                           .|.||:|:::||.:.:|  :.:::....... ..
Zfish   181 ICRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEG--TGNMFDGSILASYGN 243

  Fly   159 VVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSA 223
            |:.:.:||||..|||||..|..  ..||.||.|.:.||||.|:|||.|.|||..||:.|..||::
Zfish   244 VIVITVNYRLGVLGFLSTGDQA--AKGNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAGAS 306

  Fly   224 SVHVMMT---------TEQTRGLFHKAIMQSGCALSEW-VESPDNNWAFRLAQNLGYKGDEKD-A 277
            .|:::..         :..|:|||.:||.|||.|||.| |......:|..||:.:|.  :.|| .
Zfish   307 CVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLAKKVGC--NLKDTV 369

  Fly   278 DVLSFLSKVCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDI 342
            :::..|.|...:::  ::||:   ...|..:  ||||||     |..|:|...:.|:.:....:.
Zfish   370 EMVECLQKKHYKEL--VEQDI---QPARYHI--AFGPVI-----DGDVIPDDPQILMEQGEFLNY 422

  Fly   343 PVIVGGNSFEGLFSYQLVRKD---------PWALKNFHNIL---PREVRETSSLEGQDLLVRRLK 395
            .:::|.|..|||...:|:..:         .:|:.:|.:.|   |         ||:|:|...:|
Zfish   423 DIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSFVDDLYGYP---------EGKDILRETIK 478

  Fly   396 QLYFNNEMQESMEMFEALNIFSHRQIWHDTH------RFILA----RQSYAPKTPTYLYRFDFDS 450
            .:|.:                     |.|.|      :.:||    .|..||...|......|.|
Zfish   479 FMYTD---------------------WADRHNPETRRKTLLALFTDHQWVAPAVATADLHSSFGS 522

  Fly   451 P-HFNQFRRLVCGDRI---RGVAHADELSYLF-------YNIIASKLDKSSMEYKTIERMVGMWT 504
            | :|..|......:::   ...||.||:.|:|       ..:......|:.:....:  ::..||
Zfish   523 PTYFYAFYHHCQTEQVPPWADAAHGDEIPYVFGLPMIGPTELFPCNFSKNDVMLSAV--VMTYWT 585

  Fly   505 SFASSGNPNCPELGSAKWEAVQLKENAVEKCFNISHDLEMRDLPESDCLAVWDTFYPRESLF 566
            :||.:|:||.|.....|:  :..|.|..|:                   ..|..:..::.|:
Zfish   586 NFAKTGDPNQPVPQDTKF--IHTKPNRFEE-------------------VAWTRYNQKDQLY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	161/602 (27%)
		Aes	<117..>221	CDD:223730	42/148 (28%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	166/647 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740