Protein Alignment alpha-Est2 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 648
• Identity: 176/648 - (27%)
• Similarity: 284/648 - (43%)
• Gaps: 152/648 - (23%)

  Fly     7 WPKLIKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDK--EPYFAFEGIPYAKPPV 69
            |  |:.:..:|.....|:..|:|....::.|.||::||: ||.:.::  .|...:.|:|||.|||
Zfish    28 W--LLGLALRLALSSCQRADLTTAKHPMVTTGYGKLRGV-RKELNNEILGPVEQYLGVPYATPPV 89

  Fly    70 GDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLLGIV---------------------EGSEDCL 113
            |:.||:.|:.|..||.:.|.|  :..|:....:.|::                     ..|||||
Zfish    90 GERRFQPPEAPGSWQEIRNAT--QFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCL 152

  Fly   114 HLNVYV---------------------KALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMK- 156
            :|||||                     :.::..:..||:::|:||.|.:|  :.:::.......
Zfish   153 YLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEG--TGNMFDASVLAAY 215

  Fly   157 KPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAG 221
            ..|:.|.:||||..|||||..|.  ...||.||.||:.||||:::||.||.|||..||:.|..||
Zfish   216 GNVIVVTMNYRLGVLGFLSSGDQ--SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAG 278

  Fly   222 SASVHVMMTTEQTRGLFHKAIMQSGCALSEW-VESPDNNWAFRLAQNLGYKGDEKDADVLSFLSK 285
            ::.|::::.:..:.|||.:||.|||.|:|.| |......:...||:.:|....: .||::..|.:
Zfish   279 ASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSYSD-TADLVDCLRR 342

  Fly   286 VCARQIAAIDQDVINLDEVRSFLLFAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIPVIVGGNS 350
            ...|::  :||||   ...|..:  |||||:     |..|||...:.|:.:....:..:::|.|.
Zfish   343 KSYREL--VDQDV---QPARYHI--AFGPVV-----DGDVVPDDPEILMQQGEFLNYDILLGVNQ 395

  Fly   351 FEGL----------------FSYQLVRKDPWALKNFHNIL---PREVRETSSLEGQDLLVRRLKQ 396
            .|||                |.|        .:.||.:.|   |         ||:|:|...:|.
Zfish   396 GEGLKFVDDNEGEEGISAASFDY--------TISNFVDNLYGYP---------EGKDILRETIKF 443

  Fly   397 LYF------NNEMQESMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSP-HFN 454
            :|.      |.:|:..    ..|.:|:..| |            .||...|.....:|.|| :|.
Zfish   444 MYTDWADRDNGDMRRK----TLLALFTDHQ-W------------VAPAVATAKLHAEFQSPVYFY 491

  Fly   455 QFRRLVCGDRIR----GVAHADELSYLF-------YNIIASKLDKSSMEYKTIERMVGMWTSFAS 508
            .|.. .|....|    ..||.||:.|:|       ..:......|:.:....:  ::..||:||.
Zfish   492 TFHH-HCQTEARPEWADAAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAV--VMTYWTNFAK 553

  Fly   509 SGNPNCPELGSAKW---------EAVQLKENAVEKCF-NISHDLEMRDLPESDCLAVWDTFYP 561
            :|:||.|.....|:         |.:..|.::.:|.: :|.....:||...::.:|.|....|
Zfish   554 TGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKPRIRDNYRANKVAFWLELVP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	161/582 (28%)
		Aes	<117..>221	CDD:223730	42/125 (34%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	169/620 (27%)
		Aes	<181..>279	CDD:223730	40/101 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740