Protein Alignment alpha-Est3 and Ces1h

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 585
• Identity: 163/585 - (27%)
• Similarity: 250/585 - (42%)
• Gaps: 119/585 - (20%)

  Fly     6 VNTTSGPVLGKQCTGVYGDEYVSFE----------RIPYAQPPVGHLRFMAPLPVEPW------- 53
            ||||.|.||||         |:|.|          .:|:|:||:|.|||..|.|.|||
Mouse    26 VNTTHGKVLGK---------YISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNAT 81

  Fly    54 SQPLDCTKP---GQ--KPLQFNHYSK-QLEGVEDCLYLNVYAKE--LDSPRPLPLIVFFFGGGFE 110
            |.|..|::.   ||  ..|..|:..| :|...|||||||||...  :.:...||::|:..|||..
Mouse    82 SYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLV 146

  Fly   111 KGDP------TKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWI 169
            .|..      |...|       .:|||||:.||:...||.|..|.  ...||.|..|||.|:.||
Mouse   147 VGGASAYDGRTLSAH-------ENVVVVTIQYRLAIWGFFSTGDE--HSRGNWGHLDQLAALHWI 202

  Fly   170 KENAERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALC-TIKNLPHR 233
            ::|...|.|||.:||.||:|||..||..|:|:|.|:.|||:||.|||.|..|.... ...::..:
Mouse   203 QDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQ 267

  Fly   234 LAVNLGMESAEHVTDAMVLDFLQKLPGEKL------VRPYLLSAEEHLDDCVFQFGPMVEPYKTE 292
            :||..|.::   .|.|:::..|::...|:|      :..:.|.|:|:... .:.|.|.|    .:
Mouse   268 IAVTAGCKT---TTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKK-NYPFLPTV----LD 324

  Fly   293 HCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLP 357
            ...||..|:.:|.:...|.:|.::.          ...|...:.|..:.:.|    |.|||.:
Mouse   325 GVVLPKAPEAILAEKNFNTVPYIVG----------INKQEFGWTLPMIMEFP----PTDVKLD-- 373

  Fly   358 QALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKV--------------FWHPILKTLRS 408
               .:.:...|::..:..|.|....|.:::.|.:.....:              |..|.:...|.
Mouse   374 ---KKVISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRG 435

  Fly   409 RVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKL--DKHTPEFLT 471
            . :.:.|.||:|.|. ..|:|:        .:|:......||....|..|...:  :..:.|.:.
Mouse   436 H-RDAGAPTYMYEFQ-SRPSFS--------SELKPKTVTGDHGDEVYSVFGAPILREGSSEEEIN 490

  Fly   472 IER-MIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQKLRVW 535
            :.: |:....:|||..|||    ...||   .|...|.|...  |.|....:..:..:.:::.:|
Mouse   491 LSKMMMKFWANFARNGNPN----GQGLP---HWPEYNQKKGY--LQIGATTQQAQGLKDKEVSLW 546

  Fly   536  535
            Mouse   547  546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	162/583 (28%)
Ces1h	NP_001357759.1	COesterase	22..546	CDD:395084	162/583 (28%)