Protein Alignment alpha-Est3 and Ces2el1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 171/563 - (30%)
• Similarity: 254/563 - (45%)
• Gaps: 93/563 - (16%)

  Fly     7 NTTSGPVLGK----QCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPL 67
            ||.:|.|.|.    :.|.:   :..:|..||:|:||||.|||..|...||||...|.|......|
  Rat    35 NTHTGQVRGSLVHVKDTDI---DVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDATSHPAMCL 96

  Fly    68 QFNHY--SKQLEGV----------EDCLYLNVYA-KELDSPRPLPLIVFFFGGGFEKGDPTKELH 119
            |.::.  |:.::.:          |||||||:|| ........||::|:..||....|..:..
  Rat    97 QNDNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEGSNLPVMVWIHGGALTVGMASMY-- 159

  Fly   120 SPDYFMM---RDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPK 181
              |..|:   .||||||:.||:|.|||.|..|.  ...||.|..||:.|:.|:::|...|.|:|.
  Rat   160 --DGSMLAATEDVVVVTIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWVQQNIAHFGGNPN 220

  Fly   182 NVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNL-GMESAEH 245
            .||.||||||..||...:::|.::||||.||::||.|:....:.....:.:|:..|| |..:.:.
  Rat   221 RVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLPDLISRSSEMVYRIVANLSGCAAVDS 285

  Fly   246 VTDAMVLDFLQKLPGEKLVRPYLLSAEEHLD-DCVFQFGPMVEPYKTEHCALPNHPQELLDKAWG 309
            .|      .:|.|.|:        |..|.|| :.||:..|.|    .:...||.||||||..|..
  Rat   286 ET------LMQCLRGK--------SEAEILDINKVFKIIPAV----VDGEFLPKHPQELLASANF 332

  Fly   310 NRIPVLMSGTSFE-GLLMYARVQMAPYLLTSLKKEPE---HMLPLDVKRN-LPQALARHLGQRLQ 369
            :|:|.::...:.| |.::       |.:..|.:|..|   ..||..:|.. |...|....|..|.
  Rat   333 HRVPSIIGINNDEYGWIL-------PMIFDSAQKIEEITRKTLPTVLKSTALKMMLPPECGDLLM 390

  Fly   370 ETHFGGNDPSAMSPESLKA-YCEYASYKVFWHPILKTLRSRVKSSSASTYLYRFDFDSPTFN--- 430
            |.:.|..:    .|::|:| :.|.....:|..|.|:.  :..:.|.|..|.|.|...|..|.
  Rat   391 EEYMGDTE----DPKTLQAQFREMMGDFMFVIPALQV--AHFQRSHAPVYFYEFQHRSSFFKDVK 449

  Fly   431 --HQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMI-DMLTSFARTSNPNCKL 492
              |.:..: ||::..|     ..|| .||..:   .||.|...:.|.| ....:|||..|||
  Rat   450 PPHVKADH-GDEVFLV-----FGYL-VGDIKF---PHTEEEELLSRKIMKYWANFARHGNPN--- 501

  Fly   493 IQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQKLRVW 535
             .:.||   .|..::.......|:|..::.  ...:.::|:.|
  Rat   502 -SEGLP---HWPVMDHDDQYLQLDIQPSVG--RALKARRLKFW 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	170/561 (30%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	170/561 (30%)