Protein Alignment alpha-Est3 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 636
• Identity: 155/636 - (24%)
• Similarity: 250/636 - (39%)
• Gaps: 159/636 - (25%)

  Fly     6 VNTTSGPVLGKQC---TGVYG--DEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQK 65
            |||..|.:.|.:.   :.:.|  |:|:.   :|||.||||..||:.|.|...||...:.|.....
Zfish    71 VNTQYGKLRGARVPLHSEILGPVDQYLG---VPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPV 132

  Fly    66 PLQFNH-----------YSKQLEGV--------EDCLYLNVYAKELDSPR--------------- 96
            ..|..|           ::..|:.|        |||||||:|....|..|
Zfish   133 CPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICR 197

  Fly    97 ----------------------------PLPLIVFFFGGGFEKGDPTKELHSPDYFMMRDVVVVT 133
                                        ..|::|:..||.:.:|.... :.........:|:|:|
Zfish   198 KGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGNM-IDGSVLASYGNVIVIT 261

  Fly   134 VSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESAGAASVHYL 198
            :::|||.|||||..|.|  ..||.||.||:.|:.||.||...|.||...:|.||...||:.|..|
Zfish   262 LNFRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLL 324

  Fly   199 MLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTDAM-VLDFLQKLPGEK 262
            .|:..:|||||:||:|||:.|.|||   :...|.:....|..:...:|.|.: ::|.|:|....:
Zfish   325 TLSHHSEGLFHRAIIQSGSALSSWA---VNYQPVKYTRLLAEKVGCNVLDTLDMVDCLRKKSARE 386

  Fly   263 LVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMY 327
            ||...:..|..|:     .|||::     :...:|:.|:.|:::.......:::.....|||...
Zfish   387 LVEQDIQPARYHV-----AFGPVI-----DGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLRFV 441

  Fly   328 ARV--------------QMAPYLLTSLKKEPEHMLPLDVKRNLPQALARHLGQRLQETHFGGNDP 378
            ..|              .::.: :.||...||.      |..|.:.:      :...|.:...|
Zfish   442 ENVVDSEDGVSGNDFDFSVSDF-VDSLYGYPEG------KDTLRETI------KFMYTDWADRD- 492

  Fly   379 SAMSPESLKAYCEYASYKVFWHPILKTL------RSRVKSSSASTYLYRFDFDSPTFNHQRLKYC 437
               :||:.:                |||      ...|:.|..:..|:. .:.|||:.:....:|
Zfish   493 ---NPETRR----------------KTLVALFTDHQWVEPSVVTADLHA-RYGSPTYFYAFYHHC 537

  Fly   438 GDKLR----GVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDML-----TSFARTSNPN---- 489
            ...::    ..||.|:..|::........|.....|...:.|:..:     |:||:|.:||
Zfish   538 QSLMKPAWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNKPVP 602

  Fly   490 --CKLIQDQLPRAKE--WKPLNSKSALECLNISENIKMMELPELQKLRVWE 536
              .|.|..:..|.:|  |...|.:..| .|:|....::.:.....|:..|:
Zfish   603 QDTKFIHTKANRFEEVAWSKYNPQDQL-YLHIGLKPRVRDHYRATKVAFWK 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	154/633 (24%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	154/633 (24%)