Protein Alignment alpha-Est3 and nlgn4xa

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 609
• Identity: 153/609 - (25%)
• Similarity: 245/609 - (40%)
• Gaps: 144/609 - (23%)

  Fly     7 NTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQFNH 71
            |...|||          ::|:.   ||||.||.|..||..|.|...|....:.|:......||..
Zfish    61 NEILGPV----------EQYLG---IPYALPPTGERRFQPPEPPMSWPGIRNATQFAPVCPQFLE 112

  Fly    72 ------------YSKQLEGV--------EDCLYLNVYA---------------------KELDSP 95
                        ::..|:.|        |||||||:|.                     |::...
Zfish   113 DRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNEGGENKDIHDE 177

  Fly    96 RPL-PLIVFFFGGGFEKGDPTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGL 159
            ..| |::|:..||.:.:|.... :.........:|:|||::||:|.|||||..|.|  ..||.||
Zfish   178 NGLRPVMVYIHGGSYMEGTGNM-IDGSILASYGNVIVVTLNYRLGVLGFLSTGDQA--AKGNYGL 239

  Fly   160 KDQLLAMEWIKENAERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWAL 224
            .||:.|:.|||||.:.|.||||.||.||..|||:.|..|.|:..:|.||.|||:|||..|.|||
Zfish   240 LDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWA- 303

  Fly   225 CTIKNLPHR----LAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPM 285
              :...|.:    ||..:|....:.:.   :::.||....::|:..|:..|:.|:     .|||:
Zfish   304 --VNYQPAKYTRILAEKVGCNMLDSID---LVECLQNKNYKELIEQYITQAKYHI-----AFGPV 358

  Fly   286 VEPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPL 350
            :     :...:|:.||.|:::.......:::.....||......:                   :
Zfish   359 I-----DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGFKFVDGI-------------------V 399

  Fly   351 DVKRNLP--------QALARHLGQRLQETHFGGNDPSAMSPESLK-AYCEYASYKVFWHP----- 401
            |.:..:.        .....||        :|..:......|::| .|.::|..:   :|
Zfish   400 DSEDGVSANDFDFAVSDFVDHL--------YGYPEGKDTLRETIKFMYTDWADKE---NPETRRK 453

  Fly   402 ---ILKTLRSRVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLR----GVAHVDDHSYLWYGDFS 459
               .|.|....|..:.|:..|:. .:.|||:.:....:|..:::    ..||.|:..|::.....
Zfish   454 TLVALFTDHQWVAPAVATADLHA-QYGSPTYFYAFYHHCQSEMKPSWSDSAHGDEVPYVFGIPML 517

  Fly   460 WKLDKHTPEFLTIERMIDML-----TSFARTSNPN------CKLIQDQLPRAKE--WKPLNSKSA 511
            ...|.....|...:.|:..:     |:||:|.:||      .|.|..:..|.:|  |...|.|..
Zfish   518 GPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQ 582

  Fly   512 LECLNISENIKMMELPELQKLRVW 535
            | .|:|....::.:.....|:..|
Zfish   583 L-YLHIGLKPRVRDHYRATKVAFW 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	152/607 (25%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:395084	152/607 (25%)