Protein Alignment alpha-Est3 and ces3

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 573
• Identity: 154/573 - (26%)
• Similarity: 229/573 - (39%)
• Gaps: 150/573 - (26%)

  Fly     6 VNTTSGPVLGKQCTGVYGDEYV----------SFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCT 60
            |...||||:..:...|.| :||          .:..||:||||||..|..||.||:.|....:.|
Zfish    21 VKEDSGPVVVLKHGSVRG-QYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNAT 84

  Fly    61 KPG----QKPLQFNHYSKQL------EGV-EDCLYLNVY--AKELDSPRPLPLIVFFFGGGFEKG 112
            :..    |.|.....|:|.:      .|| |||||||||  ::..:|.: .|::|:..||....|
Zfish    85 EYSSMCLQDPNIVPKYAKSMTLELPPTGVSEDCLYLNVYTPSQRSESDK-FPVMVWIHGGALVIG 148

  Fly   113 DPTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFN 177
            .......:| ......||||.:.||:|.||:||..|.  ...||.|..||:.|::|:::|.|.|.
Zfish   149 GACMYDGTP-LAAYEKVVVVVIQYRLGILGYLSTGDQ--HAQGNWGFLDQIAALQWVQQNIEAFG 210

  Fly   178 GDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMES 242
            |||::||..|||||..|...|.|:|..:|||.:||.|||       :.|:|          |...
Zfish   211 GDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSG-------VATVK----------GYSF 258

  Fly   243 AEHVTDAMVL------DFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVE---------PYKTE 292
            .:.:|.|.|:      ||               |:.|.|..|:.:   |.|         .|:
Zfish   259 KDPLTYAKVIANITECDF---------------SSSEVLVKCIRE---MTEEQIIKAAQKKYR-- 303

  Fly   293 HCALPN----------HPQELLDKAWGNRIPVLMSGTS--FEGLLMYARVQMAPYLLTSLKKEPE 345
               ||.          .|:|:|......:||:|:..|:  |...|.:|
Zfish   304 ---LPGATVDGEFIKAQPEEILKSKDFPKIPILVGTTNHEFGWTLSHA----------------- 348

  Fly   346 HMLPLDVKRNLPQALARHLGQRLQETHFGGND-----------PSAMSPESLK-AYCEYASYKVF 398
             :||.|..:.:.   |:...|.|...:..|..           .:|.:||.:: |:.|.....:.
Zfish   349 -ILPKDWAKGMD---AKSAKQTLDFFYNAGASEANGIIADEYFKNAKTPEEIRDAFTELLGDIIM 409

  Fly   399 WHPILKTLRSRVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLD 463
            ..|.:| :.|..:.:.|..|:|.|.......|..|..:.     ...|.|:..:: :|...|...
Zfish   410 VIPSIK-VASYHRDAGAPVYMYEFQHGPSIANKFRPSFV-----KADHGDEIGFM-FGACFWDGQ 467

  Fly   464 KHTPEFLTIER------MIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKS 510
            ......||.|.      ::....:|.||.:||        |....| |:..:|
Zfish   468 VKVTGTLTEEENQLCRTVMKYWANFVRTGSPN--------PAPVPW-PVYDQS 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	154/573 (27%)
ces3	NP_001038401.1	COesterase	25..535	CDD:395084	153/569 (27%)