Protein Alignment alpha-Est3 and Nlg4

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 174/674 - (25%)
• Similarity: 249/674 - (36%)
• Gaps: 229/674 - (33%)

  Fly    29 FERIPYAQPPVGHLRFMAPLPVEPW-----SQPLDCTKPGQKPLQFN-------------HYSKQ 75
            |..:|||.||....||.......||     |.......|.:.|...|             .|.|:
  Fly    70 FLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKR 134

  Fly    76 L-----EGVEDCLYLNVYAKELDSP-------RPLPLIVFFFGGGFE--KGDPTKELHSPDYFMM 126
            |     ...||||||||:     ||       :.||:|||..|..||  .|:|........|
  Fly   135 LLPFLENQSEDCLYLNVF-----SPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASY--- 191

  Fly   127 RDVVVVTVSYRVGPLGFLSLN-DP-AVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGES 189
            .:|||||::||:|.||||:.| :| |.....|.||.||:.|:.||::|.::|.|||.:||..|..
  Fly   192 GEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG 256

  Fly   190 AGAASVHYLMLNP-KAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTD----- 248
            .|||.::|||.:| ...||||:|||.||:...||||  ::: |...|:.|..|....:.|
  Fly   257 TGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWAL--VED-PVLFAIKLAKEVNCTIPDDINRH 318

  Fly   249 -AMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVE--PYKTEHCALP-------NHPQEL 303
             ..::|.|:.:|.|.|   ||  |:....:.:..|||.|:  ..:..|..|.       |..:..
  Fly   319 HEQIVDCLRDVPLEDL---YL--ADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSS 378

  Fly   304 LDKAW-----------------------------------------GNRIPVL---MSGTS---- 320
            .|..:                                         |....||   ::|.|
  Fly   379 ADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRF 443

  Fly   321 --------FEG------LLMYARVQMAPYL----------LTSLKKEPEHMLPLDVKRNLPQALA 361
                    |||      :..|.|.....:|          .|...:..:|  |::.:.....||:
  Fly   444 SAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQH--PINTRDTAVAALS 506

  Fly   362 RHLGQRLQETHF-----------GGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSSSA 415
                    :..|           ..|.|..:|..|                   |..|...:::|
  Fly   507 --------DAQFVAPIVRAGDILAANSPPPVSSSS-------------------TAGSPGANAAA 544

  Fly   416 ST-----------YLYRFDFDSPTFNH-QRLKYCGDKLRGVAHVDDHSYLW----YGDFSWKLDK 464
            ||           |.|.||:.:...:: ||:        |..|.:|..|::    ...||
  Fly   545 STSAGSTQPSGRCYFYVFDYQTKDGDYPQRM--------GTVHGEDLPYIFGAPLVDGFS----- 596

  Fly   465 HTPEFLT------IERMIDMLTSFARTSNPNCKLIQD-QLPRAKE--------WK---PLNSKSA 511
            |.|:..|      .|.::...|:||||.|||....|| .||.:||        |:   ||:.|
  Fly   597 HFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQK-- 659

  Fly   512 LECLNISENIKMMELPELQKLRVW 535
              .|.|....::.......:|.:|
  Fly   660 --YLEIGMKPRIKNHFRAHQLSIW 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	173/672 (26%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	173/672 (26%)