Protein Alignment alpha-Est3 and Aadacl4fm1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_941064.2
• Gene: Aadacl4fm1 / 381572
• MGIID: 2685880
• Length: 407
• Species: Mus musculus
• Alignment Length: 211
• Identity: 53/211 - (25%)
• Similarity: 83/211 - (39%)
• Gaps: 45/211 - (21%)

  Fly    11 GPVLGKQCTGVYG-------DEYVSFERIPYAQPPVGH--LRFMAPLPVEPWSQPLD----CTKP 62
            |.:|...|..|.|       |.:::.:..|....||..  |.|...| ...|...|:    |:.|
Mouse     6 GFLLATVCLLVLGVNVWVLIDHFLTIDVPPSIPHPVKFRILHFCFHL-TTTWGHILEKMNICSMP 69

  Fly    63 GQKPLQFNHY------SKQLEG--VEDCLY----LNVYAKELDSPRPLPLIVFFFGGGFEKGDPT 115
                 ||..:      ||:..|  |:|..:    :.::..:..|.:|...|:||.|||...|...
Mouse    70 -----QFFCFLQDSLSSKENHGVFVKDLRFGTIPVRLFRPKAASSKPRRGILFFHGGGAMIGSLD 129

  Fly   116 KELHSPDYFMMR--DVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNG 178
            .. |:...|:.|  |.|:|:|.||..|.    .:.|::       ..|.:.|.....::.:.:..
Mouse   130 SH-HNLCTFLARETDSVLVSVGYRKLPY----YHHPSL-------YHDCINASIHFLKSLKAYGI 182

  Fly   179 DPKNVTAFGESAGAAS 194
            ||..|...|||.|.|:
Mouse   183 DPSRVVICGESIGGAA 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	53/211 (25%)
Aadacl4fm1	NP_941064.2	alpha/beta hydrolases	115..380	CDD:473884	28/96 (29%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	119..121		0/1 (0%)