Protein Alignment alpha-Est3 and Gli

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 143/556 - (25%)
• Similarity: 221/556 - (39%)
• Gaps: 142/556 - (25%)

  Fly     7 NTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWS--QPLDCTKPGQKPLQF 69
            ::|...|:| :|:...|        ||||.||....||..|.....|.  |.:|......:|:::
  Fly   165 HSTVDRVMG-ECSVFLG--------IPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRY 220

  Fly    70 NHYSKQLEGV-EDCLYLNVYAKELDS--PRPLPLIVFFFGGGFEKGDPTKELHSPDYFM------ 125
            ...:|.:..: |||||||||:.:..:  .:..|::|:..||.|.:|       :.:.|.
  Fly   221 TGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRG-------ASNLFQGHILAS 278

  Fly   126 MRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESA 190
            ..||||||::||:|.|||||..|.  ..|||.|:.||.:|:.|:.:|.|.||||..::|.||..|
  Fly   279 FYDVVVVTLNYRLGALGFLSTGDE--NSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGA 341

  Fly   191 GAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIK----NLPHRLAVNLG--MESAEHVTDA 249
            |.||...||:.|:...:..:.|.|||:.|..|||...|    |....|...||  :||:..:.:.
  Fly   342 GGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNC 406

  Fly   250 MVLDFLQKLPGEKLVRPY--LLSAEEHLDDCVFQFGPMVEPYKTEHCALPNH------------- 299
            :           :..|.:  |.:||.......|.:||:::    .:..||..
  Fly   407 L-----------RTGRSFYELGNAEFSPQVGSFPWGPVLD----HNFTLPGDDWYEGWREKDWRF 456

  Fly   300 ----PQELLDKAWGNRIPVLMSG-TSFEGLLMYARVQ-MAPYLLTSLKKEPEHMLPLDVKRNLPQ 358
                |:.|:.....||....|:| |:.|.....|:.: ::||            ..||
  Fly   457 LTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPY------------YELD------- 502

  Fly   359 ALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFW-HPILKTLRSRVKSSSASTYLYRF 422
              .|...|:::|..|..|  ..::|..:....:|  ...|| .|...|:......:..|...||.
  Fly   503 --GRFFDQKIREHVFRYN--YTLNPNGVYEAIKY--IYTFWPDPNNNTIIRDQYINMLSDLYYRA 561

  Fly   423 DFDS----------PTFNH------------QRLKYCGD----KLRGVAHVDDHSY--------- 452
            ..|.          |.:.:            |..||..|    .|.|...:|...:
  Fly   562 PVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRN 626

  Fly   453 LWYGDFSWKLDKHTPEFLTIERMIDMLTSFARTSNP 488
            :|..:     |::...|     .:...|:|||..||
  Fly   627 MWTDN-----DRNMSHF-----FMQTYTNFARYGNP 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	143/556 (26%)
Gli	NP_476602.1	COesterase	137..695	CDD:395084	143/556 (26%)
		PRK13335	818..>918	CDD:139494