Protein Alignment alpha-Est3 and Nlg3

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 171/659 - (25%)
• Similarity: 256/659 - (38%)
• Gaps: 203/659 - (30%)

  Fly     6 VNTTSGPVLG--KQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWS--------QPLDCT 60
            |:|..|.|.|  :...|.:.|...:|..:|||.||||:||||.|:....||        .|: |
Mosquito    66 VHTKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKKADRFSPV-C- 128

  Fly    61 KPGQKPLQFN-------------HYSKQL-----EGVEDCLYLNVY------AKELDSPRPLPLI 101
             |.:.|..:|             .|.::|     ...|||||||:|      ::|..|.....::
Mosquito   129 -PQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSKYAVV 192

  Fly   102 VFFFGGGFE--KGDPTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLN-DPAVGVPGNAGLKDQL 163
            ||..|..:|  .|:|........|   ..::|||::||:|.||||:.| |.....|.|.||.|.:
Mosquito   193 VFVHGESYEWNSGNPYDGSVLASY---GQILVVTINYRLGILGFLNANVDRFSKAPANYGLMDII 254

  Fly   164 LAMEWIKENAERFNGDPKNVTAFGESAGAASVHYLMLNPKA-EG-LFHKAILQSGNVLCSWAL-- 224
            .|:.||:||.|.|.||||:||..|...|||.||:|:.:... || |||:||:.||:.|..|:|
Mosquito   255 AALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAAVPEGLLFHRAIMMSGSGLAPWSLVG 319

  Fly   225 --------------CTIKNLPHRLAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHL 275
                          |: .:|||:|                :|..|:..|.|.     :||.....
Mosquito   320 EPAKFAAYVSHHVNCS-PDLPHQL----------------LLKCLRDKPLED-----ILSTSVRA 362

  Fly   276 DDCVFQFGPMVE-----------------------PYKTE-----HCALPNHPQELLDKAWGNRI 312
            .|....|||.|:                       |..|:     |..|......||.|...|::
Mosquito   363 PDFGNAFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINKL 427

  Fly   313 ---PVLMSGTSFEG---------------------LLMYARVQMAPYL----------LTSLKKE 343
               .:|:..|..|.                     |..|.|...:.:|          .|..::.
Mosquito   428 SKYDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILKNYVRSTYSFHLNEILATIVNEYTDWERP 492

  Fly   344 PEHMLPLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRS 408
            .:|  |::::....:||               :|...::|....|....|.::
Mosquito   493 VQH--PINIRDETLEAL---------------SDARIVAPAVQTADLHSADHR------------ 528

  Fly   409 RVKSSSASTYLYRFDFDSPTFNHQRLKYCGD--KLRGVAHVDDHSYLW----YGDFSWKLDKHT- 466
                   :::||.||:.:        |: ||  :.:|..|.:|..||:    .|.|:.....:|
Mosquito   529 -------NSFLYVFDYQT--------KF-GDFPQRQGCIHGEDLPYLFGAPLVGGFNHFTRNYTK 577

  Fly   467 PEFLTIERMIDMLTSFARTSNPNCKLIQDQL---PRAK--EWKPLNSKSALECLNISENIKMMEL 526
            .|....|.::...::|.||.|||.:|..|.:   .|.|  ||.|..|... :.||:....|:...
Mosquito   578 SEIALSEAVMIYWSNFIRTGNPNEQLENDHVRDRTRFKNIEWTPYESVHK-KYLNLDTKPKLKNH 641

  Fly   527 PELQKLRVW 535
            ....:|..|
Mosquito   642 YRAHRLSFW 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	170/657 (26%)
Nlg3	XP_061500330.1	None