Protein Alignment alpha-Est3 and cel.1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_955901.2
• Gene: cel.1 / 322481
• ZFINID: ZDB-GENE-030131-1201
• Length: 550
• Species: Danio rerio
• Alignment Length: 578
• Identity: 166/578 - (28%)
• Similarity: 259/578 - (44%)
• Gaps: 100/578 - (17%)

  Fly     6 VNTTSGPVLGK-QCTGVYGDEYV-SFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQ 68
            |.|..|.|.|| :..|::  .|: :|:.||:|.||   .||..|:....|...|..|...::.||
Zfish    25 VLTEGGMVQGKSRSVGLF--RYMDTFKGIPFAAPP---KRFEKPVAHPGWEGVLKTTDYRKRCLQ 84

  Fly    69 FNHYSKQLEGVEDCLYLNVY---AKELDSPRPLPLIVFFFGGGFEKGDPTKELHSPDYFM----M 126
            .|..:..:.|.|||||||::   .:.:.|  .||::||.:||.|..|.........:|..    |
Zfish    85 LNLLATDVIGSEDCLYLNIWVPQGRTVSS--NLPVMVFIYGGAFLLGGGQGANFLDNYLYDGEEM 147

  Fly   127 RD---VVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGE 188
            .|   |:|||.:||||.|||:|..|.  |:|||.||.||..|:.|:..|.:.|.|:|.|:|.|||
Zfish   148 ADRGNVIVVTFNYRVGALGFMSTGDD--GIPGNYGLWDQHAAISWVHRNIKAFGGNPDNITLFGE 210

  Fly   189 SAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLA----------VNLGMESA 243
            |||||||::.::.||.:|:..:||.|||..||.||   |...|.:.|          ::.||...
Zfish   211 SAGAASVNFQIITPKNKGMIRRAISQSGVALCPWA---ISRNPRQFAEEIATKVGCPIDSGMADC 272

  Fly   244 EHVTDAMVLDFLQKL-----PGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQEL 303
            ....|...:....||     |...:|....||             |::     :...:|:.|:.|
Zfish   273 LKRADPKAVTLAGKLKLTSSPDAPIVHNLYLS-------------PVI-----DGDFIPDEPETL 319

  Fly   304 LDKAWGNRIPV-LMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQALARHLGQ- 366
                :||...: .::|.:.....::|.:.: |.:..:|.     ..|::..:.|..||:|..||
Zfish   320 ----FGNAADIDYIAGVNDMDAHIFATIDI-PSINNALT-----TTPVEEVQALATALSRDRGQD 374

  Fly   367 ----RLQE-THFGGNDPSAMSPESLK-AYCEYASYKVFWHPILKTLRSRV-KSSSASTYLYRFDF 424
                ..|| |...|:.|   :.|.:| ...|..:..:|..|....|.... .:.||.|:.|.|..
Zfish   375 AGIATFQEYTVNWGDKP---NKEKVKQTVVELETDYMFLVPTQAALYLHTDNAKSARTFSYLFTE 436

  Fly   425 DS--PTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIER-MIDMLTSFARTS 486
            .|  |.|         ....|..|.|:..|::...|:..|. :.|....:.: ||...::||:|.
Zfish   437 SSRIPVF---------PLWMGADHADELQYVFGKPFATPLG-YFPRHRDVSKYMIAYWSNFAQTG 491

  Fly   487 NPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQKLRV---WESVCQS 541
            :||..  :.::|  ..| |..|....:.|:|:..:....:.::.:.|:   |.:|..|
Zfish   492 DPNKG--ESKVP--VTW-PEFSNPGHQYLDINNKMNKNNVKQMLRTRLVYYWTTVFAS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	163/570 (29%)
cel.1	NP_955901.2	COesterase	25..517	CDD:395084	161/549 (29%)