Protein Alignment alpha-Est3 and Aadacl2fm3

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001099906.1
• Gene: Aadacl2fm3 / 295072
• RGDID: 1560324
• Length: 401
• Species: Rattus norvegicus
• Alignment Length: 351
• Identity: 73/351 - (20%)
• Similarity: 116/351 - (33%)
• Gaps: 146/351 - (41%)

  Fly    47 PLP---VEPWS-QPLDCTKPGQK-------------PLQFNHYSKQLEGVEDC------------ 82
            |:|   .|||. :.:|.   |.|             .::|..:...|.|::|.
  Rat    22 PIPENVEEPWKVRIIDA---GMKISSLTATWLENMGLMKFEEFFGILMGIQDTKAVSDENITVID 83

  Fly    83 -----LYLNVYAKELDSPRPLPLIVFFFGGGFEKGDPTKELHSPDYFMMR------DVVVVTVSY 136
                 :.:.:|..:.:|.|..|.:::..||.|..|. .|.|  |...|.|      |.||:...|
  Rat    84 TDFNDIPVRLYLPKRESERKRPAVIYIHGGAFILGS-FKML--PYDSMNRWTANKLDAVVIAPDY 145

  Fly   137 RVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKEN--AERFNGDPKNVTAFGESAG---AASVH 196
            |:.|.....           |.|:|.:|..::..::  ..::..||..:...|:|:|   ||:|.
  Rat   146 RLAPQYLFP-----------AALEDCVLVTKFFLQDKVLAKYRVDPTRICISGDSSGGTLAATVT 199

  Fly   197 YL---------------MLNPKAEGL----------------------------------FHKAI 212
            .|               :|.|..:.|                                  ..|.|
  Rat   200 QLLQDDPEYKNKIRAQTLLYPGLQALDTLMPSFREYEHGPFLTRKVAIKMTCLYLSEDKELPKTI 264

  Fly   213 LQSGNV---------LCSWALCTIKNLPHRLAVN-------LGMESAEH-------VTDAMVLDF 254
            |::.:|         ..:|:    ..||.:...|       ||..||.|       |:..:|.|.
  Rat   265 LRNAHVPKESRHLFKFVNWS----DFLPEKYKKNHVYTEPVLGKLSASHPGLVDSRVSPLLVNDS 325

  Fly   255 -LQKLPGEKLVRPYLLSAEEHL--DD 277
             |||||     ..|:|:.|..:  ||
  Rat   326 QLQKLP-----LTYILTCEHDILRDD 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	73/351 (21%)
Aadacl2fm3	NP_001099906.1	Abhydrolase_3	107..372	CDD:400284	57/263 (22%)