Protein Alignment alpha-Est3 and Ces2a

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_653344.1
• Gene: Ces2a / 246252
• RGDID: 708353
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 156/575 - (27%)
• Similarity: 237/575 - (41%)
• Gaps: 153/575 - (26%)

  Fly     7 NTTSGPVLGK------QCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQK 65
            ||.:|.|.|.      ..:|::     :|..||:|:||||.|||..|...||||...|.|.....
  Rat    35 NTHTGQVRGSFVHVKDTKSGIH-----TFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAM 94

  Fly    66 PLQFNHYSKQLEGV-------------EDCLYLNVY----AKELDSPRPLPLIVFFFGGGFEKGD 113
            .||.:  ...|:|:             |||||||:|    |:|..:   ||::|:..|||...|.
  Rat    95 CLQTD--IMNLDGIKEMKLTVHPTPMSEDCLYLNIYTPAHAREGSN---LPVMVWIHGGGLVLGS 154

  Fly   114 PTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNG 178
            .:.. .:.......::|:|::.||:|.|||.|..|.  ...||.|..||:.|:.|:::|...|.|
  Rat   155 ASMN-DASTLAATEEIVIVSIQYRLGVLGFFSTGDQ--NARGNWGYLDQVAALRWVQQNIAYFGG 216

  Fly   179 DPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNL-GMES 242
            :...||.||.|||..||...:::|.::||||.||:|||..|....:.....:.::...|| |.|:
  Rat   217 NHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVALLPDLISDKSEVVYKTVANLSGCEA 281

  Fly   243 AEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHL--DDCVFQFGPMVEPYKTEHCALPNHPQELL- 304
            .:               .|.|:|.....:::.:  .:.||:..|.|...|    .||.||||||
  Rat   282 PD---------------SEALIRCLRAKSKQEILAINQVFKMIPGVVDGK----FLPKHPQELLA 327

  Fly   305 ----------------DKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVK 353
                            :..||  |||      |.||                    :|::....:
  Rat   328 SGDFHPVPSIIGINTDECGWG--IPV------FLGL--------------------DHIIKKITR 364

  Fly   354 RNLPQALARHLGQR---------LQETHFGGNDPSAMSPESLKAYCEYASYKVFWH--------- 400
            ..||..|.....|.         :.|.:.|..:    :||:|:        :.|.|
  Rat   365 ETLPTVLKSTAAQMMLPPECIDLIMEEYMGDTE----NPETLQ--------EQFRHMLGDFMFVI 417

  Fly   401 PILKTLRSRVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKL--D 463
            |.|:.  :..:.|.|..|.|.|. ..|:|    :|..........|.||..:: :|.:.|.:  |
  Rat   418 PALQV--AHFQRSQAPVYFYEFQ-HLPSF----IKQVRPSHVKADHGDDILFV-FGSYLWGMTFD 474

  Fly   464 KHTPEFLTIERMIDMLTSFARTSNPNCKLIQDQLP------RAKEWKPLNSKSAL 512
            ....|.|...|::....:||||.|||    .:.||      ..:::..||::.|:
  Rat   475 LTEEEELLKRRVMKYWANFARTGNPN----GEDLPHWPVLDHDEQYLQLNTQPAV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	156/575 (27%)
Ces2a	NP_653344.1	COesterase	30..537	CDD:395084	156/575 (27%)