Protein Alignment alpha-Est3 and Ces1c

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 160/594 - (26%)
• Similarity: 236/594 - (39%)
• Gaps: 151/594 - (25%)

  Fly     6 VNTTSGPVLGKQCTGVYGDEYVSFE----------RIPYAQPPVGHLRFMAPLPVEPWS------ 54
            |:||.|.||||         |||.|          .:|:|:||:|.|||..|.|.||||
  Rat    28 VDTTKGKVLGK---------YVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTT 83

  Fly    55 -QPLDCTKPG---------------QKPLQFNHYSKQLEGVEDCLYLNVYA-KELDSPRPLPLIV 102
             .|..|::.|               ..||:|:         |||||||:|: .:|.....||::|
  Rat    84 TYPPMCSQDGVVGKLLADMLSTGKENIPLEFS---------EDCLYLNIYSPADLTKNSRLPVMV 139

  Fly   103 FFFGGGFEKG--DPTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLA 165
            :..|||...|  .|...|....:   .:|||||:.||:|..|..|..|.  ...||....|||.|
  Rat   140 WIHGGGLIIGGASPYSGLALSAH---ENVVVVTIQYRLGIWGLFSTGDE--HSRGNWAHLDQLAA 199

  Fly   166 MEWIKENAERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNL 230
            :.|:::|...|.|:|.:||.||||||..||..|:|:|.|:.|||:||.:||.|
  Rat   200 LRWVQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSPLAKNLFHRAISESGVV------------ 252

  Fly   231 PHRLAVNLGMESAEHVTD--------------AMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQ 281
               |..||..::.:.|..              |||....||...|      ||.....||:.  .
  Rat   253 ---LTTNLDKKNTQAVAQMIATLSGCNNTSSAAMVQCLRQKTEAE------LLELTVKLDNT--S 306

  Fly   282 FGPMVEPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFE-GLLMYARVQMAPYLLTSLKKEPE 345
            ...::     :...||..|:|:|.:...|.:|.::.....| |.::       |.::.:|..|..
  Rat   307 MSTVI-----DGVVLPKTPEEILTEKSFNTVPYIVGFNKQEFGWII-------PTMMGNLLSEGR 359

  Fly   346 HMLPLDVKRNLPQALARHLGQRLQ----------ETHFGGNDPSAMSPESLKAYCEYASYKVFWH 400
                  :...:..:|.|.....|.          |.:..|.|..|...|.|   .:..|...|..
  Rat   360 ------MNEKMASSLLRRFSPNLNISESVIPAIIEKYLRGTDDPAKKKELL---LDMFSDVFFGI 415

  Fly   401 PILKTLRSRVKSSSASTYLYRFDFDSPTFNHQRLKYC----GDKLRGVAHVDDHSYLWYGDFSWK 461
            |.:...|| ::.:.|.||:|.|.:.....:.||.:..    ||::..|          :|....|
  Rat   416 PAVLMSRS-LRDAGAPTYMYEFQYRPSFVSDQRPQTVQGDHGDEIFSV----------FGTPFLK 469

  Fly   462 LDKHTPEFLTIERMIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMEL 526
            ......|....:.::....:|||..|||    .:.||   .|...:.|...  |.|....:..:.
  Rat   470 EGASEEETNLSKLVMKFWANFARNGNPN----GEGLP---HWPEYDQKEGY--LQIGATTQQAQK 525

  Fly   527 PELQKLRVW 535
            .:.:::..|
  Rat   526 LKGEEVAFW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	159/592 (27%)
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	159/592 (27%)