Protein Alignment alpha-Est3 and Cel

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_058693.2
• Gene: Cel / 24254
• RGDID: 2331
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 164/571 - (28%)
• Similarity: 243/571 - (42%)
• Gaps: 95/571 - (16%)

  Fly     6 VNTTSGPVLG--KQCTGVYGDEYVSFERIPYA-----QPPVGHLRFMAPLPVEPWSQPLDCTKPG 63
            |.|..|.|.|  |:.:.:.||....|:.||:|     :.|..|         ..|...|..|...
  Rat    26 VYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRH---------PGWQGTLKATDFK 81

  Fly    64 QKPLQFNHYSKQLEGVEDCLYLNVYA----KELDSPRPLPLIVFFFGGGFEKGDP------TKEL 118
            ::.||.........|.|||||||::.    |::.  ..||::|:.:||.|..|..      ...|
  Rat    82 KRCLQATITQDDTYGQEDCLYLNIWVPQGRKQVS--HDLPVMVWIYGGAFLMGSGQGANFLKNYL 144

  Fly   119 HSPDYFMMR-DVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKN 182
            :..:....| :|:|||.:||||||||||..|  ..:|||.||:||.:|:.|:|.|...|.|||.|
  Rat   145 YDGEEIATRGNVIVVTFNYRVGPLGFLSTGD--ANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDN 207

  Fly   183 VTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLP----HRLAVNLG---- 239
            :|.||||||||||....|:|..:||..:||.|||..|..||   |:..|    ..:|..:|
  Rat   208 ITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGVALSPWA---IQENPLFWAKTIAKKVGCPTE 269

  Fly   240 ----MESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHP 300
                |.....:||...|....:||         |.::|:.......|.|:|     :...:|:.|
  Rat   270 DTAKMAGCLKITDPRALTLAYRLP---------LKSQEYPIVHYLAFIPVV-----DGDFIPDDP 320

  Fly   301 QELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLP-QALARHL 364
            ..|.|.|  ..|..|......:|.| :|.|.     :.::.|..:.:...|..|.:. ..:|:.|
  Rat   321 INLYDNA--ADIDYLAGINDMDGHL-FATVD-----VPAIDKAKQDVTEEDFYRLVSGHTVAKGL 377

  Fly   365 -GQRLQ---ETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTL-RSRVKSSSASTYLYRFDF 424
             |.:..   .|.....|||..:.:  |....:.:..:|..|....| :.|..:.||.||.|.|..
  Rat   378 KGTQATFDIYTESWAQDPSQENMK--KTVVAFETDILFLIPTEMALAQHRAHAKSAKTYSYLFSH 440

  Fly   425 DS--PTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDMLTSFARTSN 487
            .|  |.:         .|..|..|.||..|::...|:..|.....:....:.||...|:||::.:
  Rat   441 PSRMPIY---------PKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSKAMIAYWTNFAKSGD 496

  Fly   488 PNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQK---LRVW 535
            ||    ....|....|.|..:::. ..|:|::.|....:.|..:   |:.|
  Rat   497 PN----MGNSPVPTHWYPYTTENG-NYLDINKKITSTSMKEHLREKFLKFW 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	163/569 (29%)
Cel	NP_058693.2	COesterase	26..542	CDD:395084	163/569 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..612
		4 X 11 AA tandem repeats, O-glycosylated region	556..599