Protein Alignment alpha-Est3 and Ces2e

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 163/582 - (28%)
• Similarity: 240/582 - (41%)
• Gaps: 133/582 - (22%)

  Fly     7 NTTSGPVLGK------QCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQK 65
            ||.:|.|.|.      ..:||:     :|..||:|:||:|.|||..|.|.||||...|.|.....
  Rat    35 NTHTGQVRGSFVHVKDTKSGVH-----TFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAM 94

  Fly    66 PLQFNHYSKQLEGV------------EDCLYLNVYA---KELDSPRPLPLIVFFFGGGFEKGDPT 115
            .|| |.....||.:            ||||||::|.   ...||  .||::|:..|||...|..:
  Rat    95 CLQ-NIDGLNLENLKIKMSRSPVSMSEDCLYLSIYTPAHTHKDS--NLPVMVWIHGGGLCWGMAS 156

  Fly   116 KELHSPDYFMM---RDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFN 177
                :.|..|:   .||||||:.||:|.|||.|..|.  ...||.|..||:.|:.|:::|...|.
  Rat   157 ----TYDGSMLAAIEDVVVVTIQYRLGILGFFSTGDE--HARGNWGYLDQVAALRWVQQNIVHFG 215

  Fly   178 GDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNL-GME 241
            |:|..||.||||||..||...:::|.::||||.||::||..|....:.....:.:.:..|| |.|
  Rat   216 GNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIYTMVANLSGCE 280

  Fly   242 SAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELL-- 304
            ..:  ::|::....:|...|.|....::.....:.|..|               ||.||.|||
  Rat   281 PVD--SEALMSCLREKSEEEMLAINNIVRTISGVVDGKF---------------LPRHPLELLAS 328

  Fly   305 -------------DKAWGNRIPVL--------MSGTSFEGLLMYARVQMAPYLLTSLKKEPEHML 348
                         ...:|..||:|        ::..:...:|....|||              ||
  Rat   329 VDFHPVPSIIGINSDEYGWIIPMLHPDSTMKEINRETMRAVLKNTAVQM--------------ML 379

  Fly   349 PLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLK-AYCEYASYKVFWHPILKTLRSRVKS 412
            |       |:.     ...|.|.:.|..:.|    ::|: .:.|.....:|..|.|:.  :..:.
  Rat   380 P-------PEC-----SDLLMEEYMGDTEDS----KTLQIQFNEMMGDFIFVIPALQV--AHFQR 426

  Fly   413 SSASTYLYRFDFDSPTFNHQRLKYC----GDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIE 473
            |.|..|.|.|...|......|..:.    ||:|..|.     .||:: |..:...:.  |.|...
  Rat   427 SHAPVYFYEFQHQSNFLKDIRPPHVKADHGDELPYVI-----GYLFW-DMKFVFTEE--EKLLSR 483

  Fly   474 RMIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQKLRVW 535
            :||....:|||..|||    .:.||   .|..|:.......|:|...:.  ...:.::|:.|
  Rat   484 KMIKYWANFARHGNPN----SEGLP---YWPALDHDEQYLQLDIQPVVG--RALKARRLKFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	162/580 (28%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:395084	162/580 (28%)