Protein Alignment alpha-Est3 and cest-28

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 155/579 - (26%)
• Similarity: 255/579 - (44%)
• Gaps: 118/579 - (20%)

  Fly     3 SLQVNTTSGPVLGKQCTGVY--GDEYV-SFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQ 64
            |.::|.|.||:.|    .||  ||:.| .:..||:|:|.|   ||..|.|...|.:..||||.|.
 Worm    14 SEKLNATCGPIQG----NVYRIGDKTVDGYLGIPFAKPLV---RFKKPEPAGTWEEVRDCTKYGP 71

  Fly    65 KPLQFNHYSKQLEGVED-------CLYLNVYAKELDSP---RPLPLIVFFFGGGFEKGDPTKELH 119
            :..|...:::.:...:|       ||.|||::|..||.   :..|::|:..|||:|..      .
 Worm    72 RCPQSGPFAEAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTRPVMVYIHGGGYECS------A 130

  Fly   120 SPDY--------FMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERF 176
            |.||        ..::||||||::||||.|||.:..|..  .|||..|.|..|.:.||:::.|.|
 Worm   131 SRDYCDYSVAGTLPLKDVVVVTLNYRVGILGFFTTGDTV--CPGNFALWDLTLGLNWIQKHIESF 193

  Fly   177 NGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKN---LPHRLAVNL 238
            .|||.|:|.||:|||||.|..|.|:|.:..||::.|:.||..||.:|:.|..:   :.:..|.:|
 Worm   194 GGDPGNITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHL 258

  Fly   239 GMESAEHVT-----DAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPN 298
            |.:.....|     .:..|:.::|:.|.::....:|:...:|||..|                |.
 Worm   259 GYDGTNSQTLFNWMKSKPLEEIEKMNGFQVPASGILAWTPNLDDDFF----------------PK 307

  Fly   299 HPQELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLD-VKRNLPQALAR 362
            ...||  :....:..::|.....|||..       .:|:    |:|..  ||: :|..:.:...:
 Worm   308 SLDEL--RIGAPKKDIMMGFAEHEGLFF-------EFLI----KDPTP--PLEALKLYVNEYYKK 357

  Fly   363 HLGQRLQETH------FGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSSSASTYLYR 421
            ..|...:.|.      :..|........:.:...::....:|...:....::.:|..: :.:||.
 Worm   358 DTGDHFEATRNKIIEFYSRNVEDTDEKSTKERLIDFVGDALFTAGVFDNAKNCLKHGN-NVWLYI 421

  Fly   422 FDFDSPT-FNHQRLKYCGDKLRGVA--HVDDHSYL----WYGDFSWKLDKHTPEFLTIERMIDML 479
            ||:.:|: |.:|.     :.:..||  |..|..|:    .|.||....::|.    .||:|..:.
 Worm   422 FDYCNPSGFGNQE-----EFMTFVAPTHCTDLRYVLGEGLYSDFQPTEEEHK----MIEKMTTIY 477

  Fly   480 TSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNIS------------ENIKMMEL 526
            ::||:..|||       ...:.||:.....:......||            :.:|.:||
 Worm   478 SNFAKYGNPN-------EHGSSEWEKFTLDNPRRHFQISYPRGKMRNDYHPDRMKFLEL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	155/579 (27%)
cest-28	NP_504691.2	COesterase	17..526	CDD:395084	151/571 (26%)