Protein Alignment alpha-Est3 and cest-30

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 159/620 - (25%)
• Similarity: 251/620 - (40%)
• Gaps: 188/620 - (30%)

  Fly     6 VNTTSGPVLG-----KQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQK 65
            :|...||:.|     |..|.:. |.|:.   ||:|:.|||.|:|..|:..|.|::|.||.:.|..
 Worm    34 LNAPCGPIRGNIYKHKNGTKIV-DGYLG---IPFAKAPVGALKFKKPVAAEKWTEPRDCYEYGPG 94

  Fly    66 PLQFNHY------SKQLEGVEDCLYLNVYA---KELDSPRPLPLIVFFFGGGFEKGDPTKELHSP 121
            ..|...:      |......|:||.|||:|   |..:.|:.||::|:.:|||:|.|..:   :..
 Worm    95 CPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGLPVLVYIYGGGYEIGFTS---YMD 156

  Fly   122 DYFM-----MRDVVVVTVSYRVGPLGFLSLNDPAVGVP-GNAGLKDQLLAMEWIKENAERFNGDP 180
            ||.:     ::||:|||::||:||||||::.|   |:. ||.||.||.||::|:::|...|.|:|
 Worm   157 DYSLTGTLPLKDVIVVTMNYRLGPLGFLTIAD---GIANGNYGLWDQTLALQWVQDNIASFGGNP 218

  Fly   181 KNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAE- 244
            ::||..|.||||.|..:|.|:|.:..||.::|..||...|::|:     .|..:.|.:..|.|:
 Worm   219 ESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAI-----RPKDVEVGVCKEFAQF 278

  Fly   245 -----------------------------HVTDAMVLDFLQKLPGEKLVRPY-LLSAEEHLDDCV 279
                                         ..|.|..:.|:....|:...:|: :|..|....|.:
 Worm   279 QGYTGTDSQSLFDWYMAQNVSKFKEVAGFQSTAAGAVPFIPNFDGDFFPKPFDILRREAPKKDAL 343

  Fly   280 FQ-----------FGPMVEPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFEGLL-------- 325
            ..           |.|                  |...|:.|          |||.:
 Worm   344 ITVVTMESVGMIIFNP------------------LFANAYNN----------FEGFINETYGPDV 380

  Fly   326 --MYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESL-K 387
              .||                      |||:.|              |.|...|.:|....:: :
 Worm   381 TDYYA----------------------DVKKKL--------------TGFYLKDVNASDKATVNR 409

  Fly   388 AYCEYASYKVFWHPILKTLRSRVKSSSASTYLYRFD-FDSPTFNHQRLKYCGDKLRGVAHVDDHS 451
            ...:|.|..||....|..::|.||..: ..||..|: |:..|.:...|.   ...:..:|..|..
 Worm   410 RVVDYVSDSVFNSGTLDAVKSYVKYGN-KVYLGSFNYFNDATKDMVELM---QPFKEASHSSDFK 470

  Fly   452 YLWYGDFSWKLDKHTPEFLTIERM--IDM----LTSFARTSNPNCKLIQDQLPRAKEWKP----- 505
            | ::|  |..:...||   |.|.|  :||    :.:|.:..:||.|      ...|.|||
 Worm   471 Y-YFG--SGVMANFTP---TDEEMEVMDMSGTLMANFVKYGDPNGK------SGTKPWKPYTILK 523

  Fly   506 --LNSKSALECLNISENIKMMELPELQKLRVWESV 538
              :..|.......:|:|.      :..:||:::.:
 Worm   524 PNMYYKIDYPTCEMSDNF------QNGRLRIYDDI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	159/615 (26%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	157/613 (26%)