Protein Alignment alpha-Est3 and cest-13

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 138/575 - (24%)
• Similarity: 227/575 - (39%)
• Gaps: 132/575 - (22%)

  Fly     3 SLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPL 67
            ::|....|..:.|.|.|  ||   .||..|.|||||||..||.|...::|         .|....
 Worm    26 TVQTPNGSATIRGIQHT--YG---TSFRGIRYAQPPVGLFRFGAARRLDP---------VGLVEA 76

  Fly    68 Q-FNHYSKQLEG---VEDCLYLNVYA-KELDSPRPLPLIVFFFGGGFEKGDPTKELH-SPDYFMM 126
            | :.:...|.:|   .||||::|||. ..:.....||:.|:..||||.:|....... .|:....
 Worm    77 QAYGNICVQGDGRTSHEDCLFINVYTPNNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNK 141

  Fly   127 RDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESAG 191
            ..:|:|:::||:||.||.|...  :..|||..:.|.:.|:.|::.....|.|||..||..|:|:|
 Worm   142 GPIVMVSINYRLGPFGFFSTRQ--MTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQSSG 204

  Fly   192 AASVHYLMLNPKAEGLFHKAILQSGN----VLCSWALCTIKNLPHRLAVNLGMESAEHVTDAM-- 250
            |.:|..|.|.|.|:.||.::|.:||:    .:.|::..| ::...:|::.||..:::...:..
 Worm   205 AEAVSTLTLTPLAKNLFKQSIHESGSAFGAAVMSYSEKT-RSTSKQLSIKLGCATSDQWDNGQSF 268

  Fly   251 --VLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELLDKAWGNRIP 313
              :|..|:.:..:|:|     :|:.                     :||.|..:     |.
 Worm   269 GTILTCLRNVTYDKIV-----AADN---------------------SLPGHRMK-----WS---- 298

  Fly   314 VLMSGTSFEGLLMYARVQMAPYLLTSLKK--------------EPEHML-PLDVKRNLPQALARH 363
            ::.........|.|..:|..|      ||              |..::| .::...|....:...
 Worm   299 IVQDNKYLTQRLEYLALQRDP------KKNVLIGDVHDEWLGWEMNNVLHNINSSHNTAHQMRDD 357

  Fly   364 LGQRLQETHF------------------GGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRV 410
            |....:.|::                  |..|.:....|:.:  .:..|..||..|   |||...
 Worm   358 LSGSYEMTYWDNKQSVLVAADNKYINNQGWTDDNHREWEARR--IQLWSEMVFIGP---TLRDAA 417

  Fly   411 --KSSSASTYLYRFDFDSPTFNHQRLKYCGDKL-RGVAHVDDHSYLWYGDFSWKLDKHTPEFLTI 472
              :....:.|||..|:.||    ..|....|.| ||..|..:..|:    ||...:.     .|.
 Worm   418 YFQYMKNNVYLYSLDWLSP----PALPLVTDPLFRGCEHTWELQYI----FSTSCNG-----FTC 469

  Fly   473 ERMIDMLTSFARTSNPNCKLIQDQLPRAK----EWKPLNSKSALECLNISENIKM 523
            ....::|.::..|:..|..:..:..|...    :|..::|.:..  |:.|.|.||
 Worm   470 TAQDEILRNYFTTTWLNFIIGGNPTPAGSPLPFKWLAMDSTNRF--LSFSPNPKM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	138/575 (24%)
cest-13	NP_741921.1	alpha/beta hydrolases	24..526	CDD:473884	138/575 (24%)