Protein Alignment alpha-Est3 and cest-19

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 167/577 - (28%)
• Similarity: 244/577 - (42%)
• Gaps: 109/577 - (18%)

  Fly     4 LQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPW-------------SQ 55
            |:||  ||.:.|::.. ..|.:|..|:.||:|.||||:|||..|.....|             .|
 Worm    28 LRVN--SGAIRGERLL-TDGQDYSVFKGIPFAMPPVGYLRFQMPKEPAKWRGVMNATQYSAMCMQ 89

  Fly    56 PLDCTKPGQKPLQFNHYSKQLEGVEDCLYLNVYAKELDSPRP-------LPLIVFFFGGGFEKGD 113
            .:|....|:......|.|      ||||||||:     ||.|       .|:|||..||.|:.|.
 Worm    90 NIDENDAGEPERYVAHVS------EDCLYLNVF-----SPTPYQYTNDTYPVIVFIHGGRFQTGS 143

  Fly   114 ----PTKELHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAE 174
                |.:.:.|  .|:.|.:|.||.:||:|||||.|..|..  :|||.||.||:.|::|:|.|||
 Worm   144 GSDIPQRAILS--NFVSRKIVFVTFNYRLGPLGFASTGDSV--LPGNIGLWDQIWALKWVKANAE 204

  Fly   175 RFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVL-----------CSWALCTIK 228
            .|.|||.|:...|...||||...|.|:|:|||||.|.:|.||:.|           .:|
 Worm   205 VFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSALQPGVVRNTQVNATW------ 263

  Fly   229 NLPHRLAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEH 293
            |:..|.... ...|:|      :||..:|...|::.:...|    |.|| ..:|.|:::....
 Worm   264 NMNDRFGCR-AFNSSE------LLDCARKRSKEEIFQYKRL----HFDD-YEEFVPIIDGVGG-- 314

  Fly   294 CALPNHPQEL-LDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLP 357
             .||..|::| |.:   .:.|:::..|..|..|....:.......:|:..|....|    ..||.
 Worm   315 -ILPEPPEQLTLHR---RKTPIVIGTTKDESSLRILLLNEKDLNFSSITWENGETL----ADNLT 371

  Fly   358 QALARHLGQRL------QETHFGGNDPSAMSPESLKAYCEYASYKVFWHPI-LKTLRSRVKSSSA 415
            ....:....||      .|..:...|||  .|||:........|..||:.. ...|.:.......
 Worm   372 LGFKQFQNHRLISQGCKSEYVWTQVDPS--FPESVLFNSLLKMYSHFWYDAPASQLATYYLKHDL 434

  Fly   416 STYLYRFDFDSPTF-NHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDML 479
            ..|||.||..|..| :..|..:..|||. :.:|.........|.:|:||:...|..:     :::
 Worm   435 PVYLYSFDHISENFYDIDRAFHGVDKLH-IFNVTPRFLNKRKDMNWQLDQRVVEIFS-----ELV 493

  Fly   480 TSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQKLRVWE 536
            .:||....|.    .:....:..|....:|. |..|:|:::      |.:|....|:
 Worm   494 ANFALYGTPT----HENDGFSFNWTSTTAKE-LSYLSITDS------PSMQVGYRWQ 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	166/574 (29%)
cest-19	NP_509187.4	alpha/beta hydrolases	24..544	CDD:473884	167/577 (29%)