Protein Alignment alpha-Est3 and cest-26

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 158/584 - (27%)
• Similarity: 251/584 - (42%)
• Gaps: 94/584 - (16%)

  Fly     3 SLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPL 67
            |.||.|.:|.|.|.:.......|...|..||:|:.|||.|||..|...|.|.....|.:.|.:..
 Worm    41 SKQVRTRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAP 105

  Fly    68 QFNHYSKQLE-GV---EDCLYLNVY-----AKELDSPRPLPLIVFFFGGGF------EKGDPTKE 117
            |.:.:.::.. ||   ||||||||:     |:|:.:... |::|:..||||      :.||.
 Worm   106 QADFFWERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLH-PVMVYVHGGGFLIDSAVKYGDE--- 166

  Fly   118 LHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKN 182
             ....|.....|||||:.||:|.|||.|..|..  .|||.||.|..:|::|:::|...|.|||:.
 Worm   167 -GIAKYLCRHGVVVVTIQYRLGLLGFFSTGDQV--CPGNLGLWDMTMALQWVRDNVHAFGGDPRK 228

  Fly   183 VTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTI-KNLPHRLAVNLGMESA--- 243
            ||.||:|||..||..|.|:|.:..|||:.:..:||..|.|:  |: ||   || ||...|.|
 Worm   229 VTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWS--TVGKN---RL-VNACREFAYRK 287

  Fly   244 ---------EHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNH 299
                     |:.:::| |:||:.....:..:..|......:........|::....::.  ||..
 Worm   288 CWDEKQARDENASESM-LEFLRTRKEREFEKRLLTRKGVDVSKIGLDLAPVIGSKPSDF--LPKS 349

  Fly   300 PQELLDKAWGNRIPVLMSGT-SFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQALARH 363
            .:||..:|....|   |.|| ..||||.   ..:.|....  :|..:.:|.|.:
 Worm   350 IEELRKEAPKKNI---MVGTCEHEGLLF---ASLGPSNFD--EKGIDKLLALLI----------- 395

  Fly   364 LGQRLQETHFGGNDPSAMSPESLKAYCEYAS----------------YK-VFWHPILKTLRSRVK 411
                .:|.|   .|..|:..|:.|.|.:..|                |. :|.:........::.
 Worm   396 ----TEENH---EDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEKMT 453

  Fly   412 SSSASTYLYRFDFDSP-TFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERM 475
            ......::|.||:.:| :|....|:   ...|...|..:.:|::.....:....:..:...::.|
 Worm   454 KLGNKVFMYSFDYCNPRSFGILSLR---APFRAATHCTELAYIFGVSIVFNYRYNESDRAMLDLM 515

  Fly   476 IDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISE-NIKMMELPELQKLRVWESV 538
            ..|.|:||:..|||.: .:|......:|:|.:.:.....|.|:| ..:|..:.:..:...|:.:
 Worm   516 TKMWTNFAKYGNPNGQ-YEDSTVFDFKWEPTSKEEPTNFLAINEKKCEMQTVYQDNRAEFWKKI 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	157/579 (27%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	157/579 (27%)