Protein Alignment alpha-Est3 and cest-2.3

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 129/563 - (22%)
• Similarity: 227/563 - (40%)
• Gaps: 143/563 - (25%)

  Fly     3 SLQVNTTSGPVLGKQCTGVY---GDEYVS-FERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPG 63
            |.::..::|.:.||.....|   |::..: |..|||.:||:|.|||..|..::.|...|: || .
 Worm    17 STRIQLSTGTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGVLE-TK-D 79

  Fly    64 QKPLQFNHYSKQL------EGVEDCLYLNVYAKE--LDSPRPLPLIVFFFGGGF--EKGDPTKEL 118
            .||...:::.|..      |..|||||.||:..:  |.: :...:::...||..  |.|...|
 Worm    80 YKPACMSYWRKTFKNGFVGEISEDCLYANVFTNQYCLQN-KNCSVMIVVHGGRLVCESGSAFK-- 141

  Fly   119 HSPDYFMM------RDVVVVTVSYRVGPLGFLSLNDPAVGVPG--NAGLKDQLLAMEWIKENAER 175
              |:.|:.      |::||||.:||:|..||...|    |..|  |..:.|.|.|::|:::..::
 Worm   142 --PEIFINNFVGQDRNIVVVTFNYRLGVFGFGVFN----GETGDTNVAMYDMLEAVKWVRKEIDQ 200

  Fly   176 FNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGM 240
            |.|:...:|..|.||||..:.....:..::||.|:.|:.|..:.........|.:. .:|.|:|.
 Worm   201 FGGNKDRITMAGHSAGAGLIVDFTSSTLSKGLLHQQIVMSAPLQDISKSANFKGMT-IVAQNVGC 264

  Fly   241 ESAEHVTDAMVLDFLQKLPGEKLVRPYLL----SAEEHL-------DDCVFQFG-PMVE-PYKTE 292
            ...|:        ..:||...::.:.||.    ||::.|       .:..|.|| |.|: .:.|:
 Worm   265 IPKEY--------GFRKLSKTQINKTYLCLQNKSAQDLLHAQLSMQQNSTFYFGSPRVDGDFITD 321

  Fly   293 HCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLP 357
                  :|..|.:  :....|:    .:|.|... ..::.:.| :|..|.:       .:|..|.
 Worm   322 ------YPDNLFN--FNTIYPI----NTFIGTTT-GELRDSLY-ITDPKND-------RIKEQLL 365

  Fly   358 QALARHLGQRLQETHFGGNDPSAMSPESLKAYC-EYASYK------------VFWHPILKTLRSR 409
            :.:..|:|..|.|           .||.....| .|  ||            .|:...:|...:.
 Worm   366 KNMCEHVGYELFE-----------KPEEFTKKCGNY--YKNGTDAQFLSDDMEFYSGAIKVANAH 417

  Fly   410 VKSSSASTYLYRFDF-----------DSPTFNH-QRLKYCGDKLRGVAHVDDHSYLWYGDFSWKL 462
             |.:::..::|.:|:           ::|:.:| :.|.|.....||.....|:
 Worm   418 -KRANSKVFMYSYDYKGAGTAFHKYLEAPSPHHSEDLIYTFGTSRGPFVAKDY------------ 469

  Fly   463 DKHTPEFLTIERMID-MLTSFARTSNPNCKLIQDQLPRAKEWK 504
                    .|||:.. ||.:|....:|:..       :.::|:
 Worm   470 --------VIERIYSGMLANFINFEDPSPS-------KTQQWR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	129/563 (23%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	129/563 (23%)