Protein Alignment alpha-Est3 and cest-2.1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 142/563 - (25%)
• Similarity: 225/563 - (39%)
• Gaps: 104/563 - (18%)

  Fly     3 SLQVNTTSGPVLGKQCTGVY---GDEY-VSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPG 63
            |.:|..::|.:.||..|..|   |:.. :.|..||:.:||.|:|||..|.|..||...|: ||.
 Worm    18 STRVQLSTGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILE-TKE- 80

  Fly    64 QKPLQFNHYSKQLE-GV-----EDCLYLNVYAKELDSPRPLPLIVFFFGGGFEKGDPTKELHSPD 122
            .||...:...|..: ||     |||||.||:..:....|....::....||....: :....:|:
 Worm    81 YKPACMSDAKKTYKNGVGGPISEDCLYANVFTNQYCMKRKNCSVMIVVHGGRILTE-SASAFNPE 144

  Fly   123 YFMM------RDVVVVTVSYRVGPLGFLSLNDPAVGVPG--NAGLKDQLLAMEWIKENAERFNGD 179
            ..:.      |::||||.:||:|..||..||    |..|  |.|:.|.|.|::|.::....|.|:
 Worm   145 ILVNNFVGQGRNIVVVTFNYRLGTFGFGVLN----GEKGDSNVGMFDMLEAVKWTRKEVHNFGGN 205

  Fly   180 PKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAE 244
            ...:|..|.|||.:.|.....:|.::|:.::.|:.||.:.....|...|          ||.:..
 Worm   206 KDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGALYQMGKLANFK----------GMTAMA 260

  Fly   245 HVTDAM--VLDFLQKLPGEKLVRPYL----LSAEEHLDDCVFQFGPMVEPYKTEHCALP------ 297
            .....:  |..| :||...::.:.|.    :||:|.||..::     |....|.:.::|
 Worm   261 QKAGCLPEVFGF-RKLSQVRIDKTYSCLRNISAQEVLDAQLW-----VLQNTTYYISVPHIDGEF 319

  Fly   298 --NHPQELLDKAWGNRIPV-LMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQA 359
              |:..|:|  |.|...|: .|.||:...|       ..|..:..||.       .|.|..|.:.
 Worm   320 LLNYSDEIL--ASGTIHPINSMIGTTTAEL-------RDPIYINDLKN-------ADKKEELLKN 368

  Fly   360 LARHLGQRLQETHFGGNDPSAMSPESLKAYCE------YASYKVFWHPILKTLRSRVKSSSASTY 418
            |..|:|..|.      .:|...|.:..|.|..      .|....|:...:|...:.. |.:...:
 Worm   369 LCEHIGYELY------TEPEEFSRKCQKFYGNGDDAQFLADDMEFYDGSIKVANAHA-SKNTKVF 426

  Fly   419 LYRFDFD--SPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMID-MLT 480
            :|.:|:.  .|.|.    ||.  :.....|.:|..|:    |.......|.:...||::.. |..
 Worm   427 MYSYDYKDAGPAFK----KYA--QAPPPHHSEDLIYV----FGTSRGNFTEKDYVIEQIYSGMFA 481

  Fly   481 SFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKM 523
            .|....||:....|    :.||:.|  .|.....::..:|..|
 Worm   482 DFVNFGNPSPSKEQ----KWKEYSP--EKREYFLIDFDKNFTM 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	142/563 (25%)
cest-2.1	NP_506508.2	COesterase	18..533	CDD:395084	142/563 (25%)