Protein Alignment alpha-Est3 and cest-33

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 149/552 - (26%)
• Similarity: 228/552 - (41%)
• Gaps: 135/552 - (24%)

  Fly     1 MESLQVNTTSGPVLGK--QCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPG 63
            :|:|:  .:.|||.|.  :...|..|.|:.   ||||:||||.|||..|:.|:.|::..||.|.|
 Worm    14 VEALK--ASCGPVRGNIYKHDDVIVDGYLG---IPYAKPPVGELRFKKPVTVDVWTEIKDCYKYG 73

  Fly    64 QKPLQFNHYSKQLEGVE-------DCLYLNVY-----AKELDSPRPLPLIVFFFGGGFEKGDPTK 116
            ...:|...: :|:.|..       .||.|||:     :.|..:.|  |::|:..|||:|.
 Worm    74 PACVQTGGF-EQIAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGR--PVMVYIHGGGYEL----- 130

  Fly   117 ELHSPDY--------FMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENA 173
             ..|.|:        ..::|||||:::||:|..|||:..|..  .|||.||.||.||::|::::.
 Worm   131 -CASSDFCAYSLSGTLPLKDVVVVSINYRLGVFGFLTTGDNV--CPGNFGLWDQTLALKWVQKHI 192

  Fly   174 ERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNL 238
            ..|.|||..||.||:|||.||...|.|:|.:..||.:.|..||...|.:|:...:|     ...:
 Worm   193 SSFGGDPNCVTVFGQSAGGASTDLLSLSPHSRDLFQRFIPISGTAHCDFAIRASEN-----QAKI 252

  Fly   239 GMESAE----HVTDAMVL---------DFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYK 290
            ..|.||    ...|:..|         :.|..:.|.|......|:...:||...|
 Worm   253 FREFAEFHGFSGRDSSALFKWYQEQSPETLSNVKGYKKSISGFLTFIPNLDGDFF---------- 307

  Fly   291 TEHCALPNHPQELLDKAWGNRIPVLMSG-TSFEGLLMYARVQMAPYLL---TSLKKEPEHMLPLD 351
                  |....||..:|...:   :|:| |.:|||::   ..|.|...   ..|...|:.:...|
 Worm   308 ------PKPLDELRKEAPKKQ---MMTGVTEYEGLML---ASMNPAFSPADVGLTLMPQGIYGKD 360

  Fly   352 VKRNLPQALARHLGQRLQETHFGGNDPS---AMSPESLKAYCEYASYKVFWHPILKTLRSRVKSS 413
            |..| |..:.:...::..|    |.|.|   ||.    |..||....:.|...:::..::..|..
 Worm   361 VVSN-PDEIQKIFYEKYVE----GVDKSDELAMR----KKLCEALGDEFFNVGVIQAAKNAAKHG 416

  Fly   414 SASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEF--------- 469
            : ..|.|.|::.:|                     |...:|.|...:|...|..|.
 Worm   417 N-EVYFYTFEYVNP---------------------DSFGMWDGMMPFKAAVHCTELRYLLGEGVY 459

  Fly   470 ----------LTIERMIDMLTSFARTSNPNCK 491
                      ..:|....:.::||:..|||.|
 Worm   460 SKFEPTEEDRKVMETTTTLFSNFAKYGNPNGK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	149/551 (27%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	148/550 (27%)