Protein Alignment alpha-Est3 and cest-24

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 156/572 - (27%)
• Similarity: 241/572 - (42%)
• Gaps: 101/572 - (17%)

  Fly     2 ESLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTK----- 61
            |:..|....|.:.|.:.....||....|..||||:||||.|||..|.|.:.|.....|.|
 Worm    94 ENAIVRVQQGLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAWEGIRKCNKYPNRS 158

  Fly    62 -----PGQKPLQFNHYSKQLEGVEDCLYLNVYAKELDSPRPLPLIVFFFGGGF--EKGDPTKELH 119
                 |..|.|...:.|      ||||||||:|.::...:..|::.:..|||:  :..:.....:
 Worm   159 IHKEMPWDKALPSANQS------EDCLYLNVFAPKIREDKKYPVLFYIHGGGYVMDSAERYTAKN 217

  Fly   120 SPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVT 184
            .....:.|:::|||..||:|.|||||..|..  .|||.||.|.|.||.|:..|...|.|||:|:|
 Worm   218 ICKLLVSREIIVVTFHYRLGFLGFLSTGDDV--CPGNYGLFDMLEAMRWVHANISSFGGDPENIT 280

  Fly   185 AFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCT---IKNLPHRLAVNLGME----- 241
            ..|:|||||:...|..:|..:|||.:.|:..||..|.||..:   |:....:.|..||.:
 Worm   281 LSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRLGWKPQLNY 345

  Fly   242 --SAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELL 304
              ..|...|  :.:|...||..||......| .....:|.....|:::..     .|| |..::|
 Worm   346 ANKREESVD--IFNFFNGLPTSKLGMTMFFS-NTIFKECQLPLAPVIDGE-----ILP-HDLKVL 401

  Fly   305 DKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQALARHLGQRLQ 369
             :.....:|.|:.|..:|.||.     .|..||...:||....:.:..::|   .|:|...:.:.
 Worm   402 -RETQEHVPSLVGGGEYEALLF-----CAIGLLRGTEKEINSAIDVLSRKN---RLSRSKIEAMT 457

  Fly   370 ETHFGGNDPSAMSPESLKA------------YCEYASYKVFWHPILKTLRSRVKSSSASTYLYRF 422
            |..:|  |..|:..:| ||            :..|.:|:     .::..:.|    ....|.|.|
 Worm   458 EKVYG--DSPALRADS-KARKMFFVQLISDIFANYGNYR-----FMRDCQQR----GVECYGYSF 510

  Fly   423 DFDSPTFNHQRLKYCG-----DKLRGVAHVDDHSYLWYGDF-SWKLDKHTPEFLTIERMIDMLTS 481
            |       ||..:..|     ....|..|..:.|||:..:: |..|..:..:.:......|..|:
 Worm   511 D-------HQSKQMWGWLQHVVPFTGGTHTSELSYLFDCNYMSAPLGMNKTDKVVSGMTADYFTN 568

  Fly   482 FARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMEL---PELQ 530
            |.:...||..  ..|||:   |:.::..        .|::|::.:   ||::
 Worm   569 FVKFGTPNGP--NSQLPK---WERISPD--------DEHMKLISIKPEPEMK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	156/572 (27%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	155/569 (27%)