Protein Alignment alpha-Est3 and cest-35.1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 160/548 - (29%)
• Similarity: 236/548 - (43%)
• Gaps: 139/548 - (25%)

  Fly     6 VNTTSGPVLGKQCTGVY--GDEYV-SFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPL 67
            :|.:.||:.|    .:|  .|:.| .:..||:|:.|:|.|||...:..|.|::||||.|.|....
 Worm    17 LNASCGPIRG----NIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGPGCP 77

  Fly    68 QFNHYSKQL--------EGVED-CLYLNVYA---KELDSPRPLPLIVFFFGGGFEKGDPTKELHS 120
            |.......:        |..|| ||.|||:|   |..:.|..||:||:|:|||||.|..:.   .
 Worm    78 QSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEVGFSSM---F 139

  Fly   121 PDYFM-----MRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDP 180
            .||.:     ::||::||.:||:|||||.:..|..  ..||.||.||.||::|::::.:.|.|||
 Worm   140 DDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDV--SRGNWGLWDQALALQWVQKHIKSFGGDP 202

  Fly   181 KNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCT--IKNL-------PHRLAV 236
            .|||..|.|||.|||.:|.|:|.|...|||.|..||...|.:.:.:  ::.|       .|..|.
 Worm   203 SNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRSKDVEGLIFREFAKHHGYAG 267

  Fly   237 NLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQ 301
            | ..||..|...:...:...|..|.|    |..|.       :|.|             :||:..
 Worm   268 N-DSESLLHWYQSQDAEIFLKAEGFK----YPASG-------MFSF-------------VPNYDG 307

  Fly   302 ELLDKAWGN------RIPVLMSGTSFEGL---LMYARVQMAPYLLTS-------------LKKEP 344
            :...|.:..      ::..::|...:|||   ..|...:....:||:             :||..
 Worm   308 DFFPKPFDELRKEAPKLDAIVSVAEYEGLGFEEFYPGQKSPQEVLTAALGPEVVRNREEVVKKAV 372

  Fly   345 EHMLPLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSR 409
            |..|     .|:.......:|::|.|. ||.               .|.|..||     .|:||.
 Worm   373 EAYL-----ENIEDKSGEKIGKKLVEI-FGD---------------YYFSVGVF-----DTVRSL 411

  Fly   410 VKSSSASTYLYRFDFDSP----TFNHQRLKYCGDKLRGVAHVDDHSYL---WYGDFSWKLDKHTP 467
            .|..: :.||..|::.:|    .|...|      .....:|..|..|:   ..|:|| |.|:
 Worm   412 AKYGN-NVYLSSFNYFNPETPIMFGENR------PFNAASHGCDIRYILGDGIGEFS-KEDR--- 465

  Fly   468 EFLTIERMIDM----LTSFARTSNPNCK 491
                  :::||    ||:||:..|||.|
 Worm   466 ------KVMDMMGTYLTNFAKYGNPNGK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	160/548 (29%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	160/548 (29%)