Protein Alignment alpha-Est3 and cest-35.2

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 163/544 - (29%)
• Similarity: 242/544 - (44%)
• Gaps: 134/544 - (24%)

  Fly     7 NTTSGPVLGKQCTGVY--GDEYVS-FERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQ 68
            |.:.||:.|    .||  ||:.|: :..||:|:.|:|.|||...:..|.|:|||||.|.|....|
 Worm    18 NASCGPIRG----NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCPQ 78

  Fly    69 ------------FNHYSKQLEGVED-CLYLNVYA---KELDSPRPLPLIVFFFGGGFEKGDPTKE 117
                        .||     :..|| ||.|||:|   |..:.|...|::|:|:|||||.|..:.
 Worm    79 SAALGALMVSQATNH-----DFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSSM- 137

  Fly   118 LHSPDYFM-----MRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFN 177
              ..||.:     ::||::||.:||:|||||.:..|..  ..||.||.||.||::|::::.:.|.
 Worm   138 --FDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDV--ARGNWGLWDQALALQWVQKHIKSFG 198

  Fly   178 GDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCT--IKNLPHRLAVN--- 237
            |||.|||..|.|||.|||.:|.|:|.|...|.|.|..||...|.:.:.:  ::.|..|...|
 Worm   199 GDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANHHG 263

  Fly   238 -LGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDC----VFQFGPMVEPYKTEHCALP 297
             .|.:|..      :|.:.|....|     ..|.||.:  .|    :|.|             :|
 Worm   264 YTGNDSKS------LLQWYQSQDSE-----IFLKAEGY--KCPASGMFSF-------------VP 302

  Fly   298 NHPQELLDKAWGN------RIPVLMSGTSFEGL---LMYARVQMAPYLLTSLKKEPEHMLPL--- 350
            |...:...|.:..      ::..::|...:|||   ..||.           :|.|:.||..
 Worm   303 NFDGDFFPKPFDELRKEAPKLGAIVSIGEYEGLGFEDFYAG-----------QKTPQQMLSAALG 356

  Fly   351 -DVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESL-KAYCEYASYKVFWHPILKTLRSRVKSS 413
             :|.||..:.:.|.....|:.   |||:    :.|:: |...|......|......|:||.||..
 Worm   357 PEVVRNREEVVKRAAESYLKN---GGNE----NEENIAKTLVEIFGDYYFSVGAFDTVRSLVKYG 414

  Fly   414 SASTYLYRFDFDSP----TFNHQRLKYCGDKLRGVAHVDDHSYLW---YGDFSWKLDKHTPEFLT 471
            : :.|||.|::.:|    .|...|      ......|..|..|::   .|:|| |.|:
 Worm   415 N-TVYLYSFNYFNPNTPIVFGKNR------PFNAANHGSDLRYIFGEGTGEFS-KEDR------- 464

  Fly   472 IERMIDML----TSFARTSNPNCK 491
              :::||:    |:||:..|||.|
 Worm   465 --QVMDMMGTYHTNFAKYGNPNGK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	163/544 (30%)
cest-35.2	NP_504398.1	COesterase	18..517	CDD:395084	163/544 (30%)