Protein Alignment alpha-Est3 and cest-32

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 145/524 - (27%)
• Similarity: 231/524 - (44%)
• Gaps: 88/524 - (16%)

  Fly     3 SLQV-NTTSGPVLGKQCTGVY--GDEYVS-FERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPG 63
            ||:| |.:.|||:|    .:|  .|:.|: :..||:|:.|:..|||..|:..|.|::||:|.|.|
 Worm    13 SLEVLNASCGPVIG----NIYRHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKYG 73

  Fly    64 QKPLQFNHYSKQL------EGVED-CLYLNVYA---KELDSPRPLPLIVFFFGGGFEKGDPTKEL 118
            ....|..|....|      |..|| ||.||::|   |..:.|..||::|:|.|||||.|..:.
 Worm    74 PGCPQSGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSSM-- 136

  Fly   119 HSPDYFM-----MRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNG 178
             ..||.:     ::||:|||.:||||||||::..|..  ..||.||.||.||::|::|:.:.|.|
 Worm   137 -FDDYSLSGTLPLKDVIVVTANYRVGPLGFMTTGDEV--SRGNYGLWDQTLALKWVQEHIKSFGG 198

  Fly   179 DPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIK---NLPHRLAVNLGM 240
            :|..||..|.|||..|...|.|:|.:..|||:.:..||:..|.:::.|.:   .:....|.:.|.
 Worm   199 NPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGY 263

  Fly   241 ESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQ----FGPMVEPYKTEHCALPNHPQ 301
            |..:   ...:|::.:..|..|                 ||    |......:.|   .:||...
 Worm   264 EGED---SESLLEWYKSQPLSK-----------------FQETATFEKKASGFLT---FIPNFDG 305

  Fly   302 ELLDKAWGN------RIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQAL 360
            :...|.:..      ::..:.:...:|||......|.....:..:|..    ...||..|
 Worm   306 DFFPKPFDELSREAPKLDAMATVDEYEGLGFLTMFQSRRNDMDIIKSS----FGSDVVEN----- 361

  Fly   361 ARHLGQRLQETHFGG---NDPSAMSPESLKAYCEYASYKVFWHPI--LKTLRSRVKSSSASTYLY 420
            |..:.:|:.|.:...   ||..|:....::...:      .|..|  |:|:::..|..| :.||.
 Worm   362 AVDVQKRIMEFYMKNIDKNDDKAVEKRLIQLISD------SWFNIGALETVKTSTKYGS-NAYLG 419

  Fly   421 RFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDMLTSFART 485
            .||:.:...|.....:.  ..:...|..:..|: .|:...|......||..|:.|..:..:|.:.
 Worm   420 SFDYYNMGSNDPYATWF--PFKAANHGSELKYM-LGEGMGKFSPIEEEFKVIDMMGTLTANFVKY 481

  Fly   486 SNPN 489
            .|||
 Worm   482 GNPN 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	145/524 (28%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	143/521 (27%)