Protein Alignment alpha-Est3 and cest-5.1

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 124/515 - (24%)
• Similarity: 213/515 - (41%)
• Gaps: 105/515 - (20%)

  Fly     2 ESLQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKP 66
            :||.::|:.|.:.|.:    .|| |..|::||:|:||||:|||..|.....|.......:.|  |
 Worm    17 DSLIIHTSFGHLEGAE----IGD-YHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYG--P 74

  Fly    67 LQFNHYSK----QLEGVEDCLYLNVY-AKELDSPRPLPLIVFFFGGG--FEKGDPTKELHSPDYF 124
            ...::.||    |....||||::|:: :|:....|...:.|:..|||  ::......:....|.|
 Worm    75 ACMSNSSKTKSPQKWVDEDCLHVNIFTSKKCLKSRNCAIAVYIHGGGLTYDSAVMFNDTVLLDTF 139

  Fly   125 MMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGES 189
            :.|||::|...:|:|.....::::..| .|.|..|.|..||:|::|.....|.|:.:.:|.||.|
 Worm   140 VKRDVILVIPGFRLGIFSHFTVHNQNV-APNNLALYDITLALEFVKSEIHSFGGNSQKITLFGHS 203

  Fly   190 AGAASVHYLMLNPKAE---GLFHKAILQSGNV--------------LCSWALCTIKNLPHRLAVN 237
            .|......:..:.:..   .||.:||:.||..              ...:|.|::.     |.:.
 Worm   204 YGGGLASMMTFSSEINRDLSLFQQAIVMSGGFYFEELKDHIEGTKRFVEYANCSVP-----LKLE 263

  Fly   238 LGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMV--EPYKTEHCALPNHP 300
            ..||.::.  :..::..||||.|.:|:|...|..::...|    ||.::  ||      ..|:..
 Worm   264 RKMERSQQ--EMYMMKCLQKLSGMELLRIQRLLEDKGYPD----FGGVILREP------LFPDVK 316

  Fly   301 Q-ELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVK-RNLPQALARH 363
            : |||...  ..||:|...|:.|......:|....||      |.|:....|.| ||..::...:
 Worm   317 KFELLKSP--KNIPMLTGCTNLEFDHESIKVPFGKYL------EFENPDECDEKYRNDVESGVEN 373

  Fly   364 LGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSSSASTYLYRFDFDSPT 428
            .|....:|.      ..:.|                   ||...:.:..::.:.|||.:.:.
 Worm   374 RGNHTDKTQ------GIILP-------------------LKLQINNLLENNVTAYLYEYTYP--- 410

  Fly   429 FNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDMLTSFARTSNP 488
             .|.|            |.||.||: .|..:::.|::......:.:  ||:.:|.:...|
 Worm   411 -KHGR------------HTDDLSYI-MGVHAFEKDENEVHLEQVYK--DMVINFIKLGEP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	124/515 (24%)
cest-5.1	NP_501022.3	alpha/beta hydrolases	17..495	CDD:473884	124/515 (24%)