Protein Alignment alpha-Est3 and ace-4

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 598
• Identity: 143/598 - (23%)
• Similarity: 240/598 - (40%)
• Gaps: 132/598 - (22%)

  Fly    13 VLGKQCTGVYGDEYV-------SFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQF- 69
            ||..:...:.|.|:.       :|..:|:|:|.|...||..|...:.|....|.|||.....|.
 Worm    28 VLETKLGDIKGTEFFFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDATKPANACFQTR 92

  Fly    70 NHYSKQLEG----------VEDCLYLNVYAKELDSPRPLPLIVFFFGGGFEKGDPTKELHSPDYF 124
            ::|:....|          .|||||||::|..  ....|.::|:||||||..|.|:..::.....
 Worm    93 DNYNTSFWGSEMWNANTQISEDCLYLNIWAPA--DAYNLTVMVWFFGGGFYSGSPSLSIYDGKAL 155

  Fly   125 -MMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGE 188
             ..::|:||.::||:||.|||.|..|  ..|||.||.||.||:.|:::|...|.|:|..|..||:
 Worm   156 TSTQNVIVVNINYRLGPFGFLYLGHP--DAPGNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFGQ 218

  Fly   189 SAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTDAMVLD 253
            ||||||:...::.|.:.|||..||||||::..:||:    |.|
 Worm   219 SAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAI----NSP---------------------- 257

  Fly   254 FLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELLDKAWGNRIP----- 313
            |..|...|||:.  |:...:...|            .:..|.....|::|....|...:.
 Worm   258 FRAKQKSEKLLE--LVGCNKTTVD------------TSMACLRLVSPEQLSLSTWNISLTYLEFP 308

  Fly   314 -VLMSGTS--FEGLLMYARVQMAPY-----LLTSLKKEPEHMLPLDVKRNLPQALARHLGQRLQE 370
             |::|...  |..|..:|.::...:     |:..:.|:..:...:   ..|||...:.....|..
 Worm   309 FVIVSRDKHFFGHLDAHAALREGDFNRDVNLMIGMNKDEGNYWNI---YQLPQFFDKADPPELNR 370

  Fly   371 THFGG--NDPSAMSPESLKAYCEYA-----------------------------SYKVFWHPILK 404
            |.|..  :...::.|:.:::..:|.                             |....|  :..
 Worm   371 TEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDYFFSCDSLW--LAD 433

  Fly   405 TLRS--RVKSSS-----ASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKL 462
            ..||  ||||||     ...::|.|. .|.:.|.      ..|..|..|..:..|::....|:..
 Worm   434 QFRSIPRVKSSSPQRKPGKVFVYHFT-QSSSANP------WPKWTGAMHGYEIEYVFGIPLSYSK 491

  Fly   463 DKHTPEFLTIERMIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNI--SENIKMME 525
            :....|.:...:::....|||:...|..:::::    ::.|...|.::....:.:  ..||:.::
 Worm   492 NYKRREQIFSRKIMQFWASFAKNGTPKLRVLKN----SEHWPEFNEQNHYRWMQLRSGSNIRPIK 552

  Fly   526 LPELQKLRVWESV 538
            ..:..:.:.|..|
 Worm   553 PKKQVECQFWRRV 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	141/593 (24%)
ace-4	NP_496962.1	COesterase	28..562	CDD:395084	141/593 (24%)