Protein Alignment alpha-Est3 and nlgn4x

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 150/612 - (24%)
• Similarity: 252/612 - (41%)
• Gaps: 156/612 - (25%)

  Fly    11 GPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQFNH---- 71
            |||          ::|:.   :|||.||.|..||..|.|...|:...:.|:......||..
 Frog    68 GPV----------EQYLG---VPYASPPTGERRFQPPEPPSSWTGIKNATQFAPVCPQFLDERSL 119

  Fly    72 --------YSKQLEGV--------EDCLYLNVYA-----------------------KELDSP-R 96
                    ::..|:.|        |||||||:|.                       :::..| .
 Frog   120 LNDMLPIWFTANLDTVVSYVQDQNEDCLYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNN 184

  Fly    97 PLPLIVFFFGGGFEKGDPTKELHSPDYFMMR-DVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLK 160
            ..|::|:..||.:.:|  |..:......... :|:|:||:||:|.|||||..|.|  ..||.||.
 Frog   185 KKPVMVYIHGGSYMEG--TGNMIDGSILASHGNVIVITVNYRLGVLGFLSTGDQA--AKGNYGLL 245

  Fly   161 DQLLAMEWIKENAERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWALC 225
            ||:.|:.||:||...|.||||.||.||..|||:.|..|.|:..:||||.|||:|||..|.|||
 Frog   246 DQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA-- 308

  Fly   226 TIKNLPHR----LAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMV 286
             :...|.:    ||..:|.:..:.:.   :::.|:....::|::..:..|..|:     .|||::
 Frog   309 -VNYQPAKYTRILADKVGCDMLDTID---LVECLRDKNYKELIQQSITPATYHI-----AFGPVI 364

  Fly   287 EPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMY-------ARVQMAPY------LLT 338
                 :...:|:.||.|:::.......:::.....|||...       ..|.::.:      .:.
 Frog   365 -----DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGMVDNEDGVSLSDFDFSVSNFVD 424

  Fly   339 SLKKEPEHMLPLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPIL 403
            :|...||.      |..|.:.:      :...|.:...:    :||:.:
 Frog   425 NLYGYPEG------KDTLRETI------KFMYTDWADKE----NPETRR---------------- 457

  Fly   404 KTL------RSRVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLRGV----AHVDDHSYLW---- 454
            |||      ...|..:.|:..|:. .:.|||:.:....:|..:::..    ||.|:..|::
 Frog   458 KTLVALFTDHQWVAPAVATADLHA-RYGSPTYFYAFYHHCQSEMKPTWADSAHGDEVPYVFGIPM 521

  Fly   455 YGD---FSWKLDKHTPEFLTIERMIDMLTSFARTSNPN------CKLIQDQLPRAKE--WKPLNS 508
            .|.   |:....|:  :.:....::...|:||:|.:||      .|.|..:..|.:|  |...:.
 Frog   522 IGPTELFNCNFSKN--DVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKPNRFEEVAWSKYDP 584

  Fly   509 KSALECLNISENIKMMELPELQKLRVW 535
            |..| .|:|....::.:.....|:..|
 Frog   585 KDQL-YLHIGLKPRVRDHYRATKVAFW 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	149/610 (24%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	149/610 (24%)