Protein Alignment alpha-Est3 and cel.2

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001120027.1
• Gene: cel.2 / 100144991
• XenbaseID: XB-GENE-1217488
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 573
• Identity: 163/573 - (28%)
• Similarity: 242/573 - (42%)
• Gaps: 98/573 - (17%)

  Fly     6 VNTTSGPVLG-KQCTGVYGDEYVS-FERIPYAQPPVGHLRFMAPLPVEP------WSQPLDCTKP 62
            |:|..|.|.| .:..||...:|:. |:.||:|.|         |.|.|.      ||..|.....
 Frog    25 VHTEGGFVEGTNKKIGVVFPDYIDIFKGIPFAAP---------PKPFEKAEKHPGWSGTLQAKDY 80

  Fly    63 GQKPLQFNHYSKQLEGVEDCLYLNVYAKELDS--PRPLPLIVFFFGGGFEKGDP------TKELH 119
            ..:.||.......:.|..|||||||:..:..|  ...||::|:.|||||..|..      :..|:
 Frog    81 KPRCLQATITQDNVFGSLDCLYLNVWVPQTRSQVSTNLPVMVWIFGGGFLLGSGQGANFLSNYLY 145

  Fly   120 SPDYFMMR-DVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNV 183
            ..:...|| .|:|||.:||||||||||..|.  ..|||.||.||.:|:.|:|.|...|.|||.|:
 Frog   146 DGEEVAMRGKVIVVTFNYRVGPLGFLSTGDS--NAPGNYGLWDQHMAIAWVKRNIAAFGGDPNNI 208

  Fly   184 TAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNVLCSWA-----LCTIKNLPHRLA--VNLGME 241
            |.||||||.|||....|.|...||..:||.|||..||.||     |...|:|..:|.  ||...|
 Frog   209 TLFGESAGGASVSLQTLTPYNVGLIKRAISQSGVGLCPWAIQRDPLTWAKSLASKLGCPVNNTKE 273

  Fly   242 SAEHV--TDAMVLDFLQKLPGEKLVRP---YLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQ 301
            .|:.:  ||...|....:|....|..|   ||            .:.|::     :...:|:.|:
 Frog   274 LADCLRNTDPGALTIAYQLQLFNLEYPLVHYL------------AYSPVI-----DGDFIPDEPR 321

  Fly   302 ELLDKAWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNLPQAL------ 360
            .|...|.|  :..:....:.:|.| :|.|.: |.:     .:|.|.:..:..:.:.:.|
 Frog   322 NLFSNAAG--VDYIAGVNNMDGHL-FAGVDL-PAI-----NQPLHKISTEQVQKVVRGLTLAKGV 377

  Fly   361 -ARHLGQRLQETHFGGNDPSAMSPESLK-AYCEYASYKVFWHPILKTLRSRVKSS-SASTYLYRF 422
             |..:...|....:|.|.    |.|.:| ...|..:..:|.....:.|....::: .|.||.|.|
 Frog   378 PALDIAYDLYTAGWGTNP----SQEDMKRTVVEVETDYIFLVATQEALALHYQNAKGAKTYSYMF 438

  Fly   423 DFDS--PTFNHQRLKYCGDKLRGVAHVDDHSYLWYGDFSWKLDKHTPEFLTIERMIDMLTSFART 485
            ...|  |.:         ....|..|.:|..:::...||..|.....:....:.||...|:||.|
 Frog   439 SHPSRMPVY---------PSWMGADHAEDLQFMFGKPFSTPLAYRPRDRDVAQYMIAYWTNFAAT 494

  Fly   486 SNPNCKLIQDQLPRAKEWKPLNSKSALECLNISENIKMMELPELQK---LRVW 535
            .:|:..  :..:|  ..|...::::. :.|.|:..|....:.:..:   :|.|
 Frog   495 GDPSKG--ESSIP--TPWLAYSTENG-QYLEINHKINYQSMKQSLRSPYVRFW 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	162/571 (28%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:395084	162/571 (28%)