Protein Alignment alpha-Est3 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 612
• Identity: 157/612 - (25%)
• Similarity: 246/612 - (40%)
• Gaps: 153/612 - (25%)

  Fly     7 NTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCTKPGQKPLQFNH 71
            |...|||          ::|:.   :|||.||||..||..|.....|.:..:.|       ||..
Zfish    70 NEILGPV----------EQYLG---VPYATPPVGERRFQPPEAPGSWQEIRNAT-------QFAP 114

  Fly    72 YSKQ-LEGV-------------------------EDCLYLNVYAKELDSP--------------- 95
            ...| :.||                         |||||||||....|.|
Zfish   115 VCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRD 179

  Fly    96 ------RPLPLIVFFFGGGFEKGDPTKELHSPDYF-MMRDVVVVTVSYRVGPLGFLSLNDPAVGV 153
                  |..|:::|..||.|.:|  |..:...... ...:|:|||::||:|.|||||..|.:  .
Zfish   180 EDIRDRRKKPVMLFIHGGSFMEG--TGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSSGDQS--A 240

  Fly   154 PGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESAGAASVHYLMLNPKAEGLFHKAILQSGNV 218
            .||.||.||:.|:.|:.||...|.|||:.:|.||..|||:.|:.|:|:..:||||.:||.|||:.
Zfish   241 KGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSA 305

  Fly   219 LCSWALCTIKNLPHR--LAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQ 281
            :.||:: ..:.|.:.  ||..:|...::   .|.::|.|::....:||...:..|..|:     .
Zfish   306 ISSWSV-NYRPLMYTKILAKKVGCSYSD---TADLVDCLRRKSYRELVDQDVQPARYHI-----A 361

  Fly   282 FGPMVEPYKTEHCALPNHPQELLDKAWGNRIPVLMSGTSFEGLLMY------ARVQMAPY----- 335
            |||:|     :...:|:.|:.|:.:.......:|:.....|||...      ..:..|.:
Zfish   362 FGPVV-----DGDVVPDDPEILMQQGEFLNYDILLGVNQGEGLKFVDDNEGEEGISAASFDYTIS 421

  Fly   336 -LLTSLKKEPEHMLPLDVKRNLPQALARHLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFW 399
             .:.:|...||..   |:.|..         .:...|.:...|...|..::|.|
Zfish   422 NFVDNLYGYPEGK---DILRET---------IKFMYTDWADRDNGDMRRKTLLA----------- 463

  Fly   400 HPILKTLRSRVKSSSASTYLYRFDFDSP----TFNHQRLKYCGDKLR----GVAHVDDHSYLWYG 456
               |.|....|..:.|:..|:. :|.||    ||:|    :|..:.|    ..||.|:..|::..
Zfish   464 ---LFTDHQWVAPAVATAKLHA-EFQSPVYFYTFHH----HCQTEARPEWADAAHGDEIPYVFGV 520

  Fly   457 DFSWKLDKHTPEFLTIERMIDML-----TSFARTSNPN------CKLIQDQLPRAKE--WKPLNS 508
            ......:.....|...:.|:..:     |:||:|.:||      .|.|..:..|.:|  |...:|
Zfish   521 PMVGATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSS 585

  Fly   509 KSALECLNISENIKMMELPELQKLRVW 535
            |.. :.|:|....::.:.....|:..|
Zfish   586 KDK-QYLHIGLKPRIRDNYRANKVAFW 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	156/610 (26%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	156/610 (26%)