Protein Alignment alpha-Est4 and Ache

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 164/551 - (29%)
• Similarity: 243/551 - (44%)
• Gaps: 94/551 - (17%)

  Fly    11 VVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ- 74
            :|:...|::|||.||: ......||.|||:|.||:|:.||..|...:||.||.|.:...:.|.|
  Rat    40 LVRVRGGQLRGIRLKA-PGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQY 103

  Fly    75 VSTLTKEVEG----------SEDCLYLNI-SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDY 128
            |.||....||          ||||||||: :.......|.||:::|:||.|..|.||...:...:
  Rat   104 VDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRF 168

  Fly   129 FMK-ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFG 192
            ..: |..|.:|:.:|:|..|||:| ....:.|||.||.|..|||:|::.|.|.|.|||..:|:||
  Rat   169 LAQVEGTVLVSMNYRVGTFGFLAL-PGSRDAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFG 232

  Fly   193 HSSGSMTVQLLLASPQSEGLFHRAILLAG---------FSMELNRLPQMEYRLAK-HLGYEGDNV 247
            .|:|:.:|.:.:.|..|..|||||:|.:|         .:.|..|...:..||.. ..|..|.|
  Rat   233 ESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGN- 296

  Fly   248 DSQVLEFLLKADPALIVSADFFTPLEKRQGHNMP--------FKPSIES---YSTPNAVL-LAEP 300
            |::::. .|:..||        ..|...:.|.:|        |.|.::.   ..||.|:: ..:.
  Rat   297 DTELIS-CLRTRPA--------QDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDF 352

  Fly   301 IDLQRTTWSNRIPIILGANSGEGMSIF------SFVKMNPSWLKEFQCNPERVLPWTLRNRCDPG 359
            .|||         :::|....|| |.|      .|.|.|.|.:...|        :....|....
  Rat   353 QDLQ---------VLVGVVKDEG-SYFLVYGVPGFSKDNESLISRAQ--------FLAGVRIGVP 399

  Fly   360 QRRQL-GQALIHHFCE-------AHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTY 416
            |...| .:|::.|:.:       ||    ..|..:.:|.  .|..|..:.:| ..||....|..|
  Rat   400 QASDLAAEAVVLHYTDWLHPEDPAH----LRDAMSAVVG--DHNVVCPVAQL-AGRLAAQGARVY 457

  Fly   417 LYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFA 481
            .|.|:..:....:       ....||.|..|:.:||.||....|:.:..|....:||:..:..||
  Rat   458 AYIFEHRASTLTW-------PLWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMKYWTNFA 515

  Fly   482 ATSDPNAPLTKSLVDWKPVTRFGKRMV-LNI 511
            .|.|||.|.......|.|.|...::.| ||:
  Rat   516 RTGDPNDPRDSKSPRWPPYTTAAQQYVSLNL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	164/551 (30%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	164/551 (30%)