DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and nceh1b.2

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:XP_001335382.3 Gene:nceh1b.2 / 797436 ZFINID:ZDB-GENE-161207-1 Length:409 Species:Danio rerio


Alignment Length:444 Identity:87/444 - (19%)
Similarity:141/444 - (31%) Gaps:140/444 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 LLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVSTLTKEVEGSED 87
            :|:.:....|:|.:           |...:|.|:..:....|..|.......:.......||.:.
Zfish    40 ILRGVMHVSFFAHN-----------LGLSQPFDVAKYAASWDEIKAPQSSQTIRVTETYFEGVQA 93

  Fly    88 CLYLNISVKTLNGDPMPVM----VYIHGGAFKGGDSSR-----RAWGPDYFMKE--NVVYISIGH 141
            .::     ::...|..|.:    :|.|||.:..|....     :.|.    |.|  :.|.|||.:
Zfish    94 QVF-----ESTQADQEPYLKRGIIYFHGGGWTLGSGKMQTYYLQCWS----MAEQLDAVVISIEY 149

  Fly   142 RLGPLGFLSLNDPDLEVPGNAGLKDVILA--LRWIRANAANFNGDPERITIFGHSSGSMTVQLLL 204
            ||.|    ....||.........|.::.|  ||       .:..||:|:.:.|.|:|:   .|..
Zfish   150 RLTP----EARFPDQYNEAVQASKHILTAEVLR-------RYFIDPKRVAVSGDSAGA---NLAA 200

  Fly   205 ASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFF 269
            |..|...|.|.|.:  .|.::....|                    ||:.|           ||.
Zfish   201 AVAQQMALDHSASI--KFKVQALLYP--------------------VLQAL-----------DFN 232

  Fly   270 TPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNP 334
            ||..::.| |:|              :|..|:                      |:.|       
Zfish   233 TPSYQQNG-NIP--------------ILHRPL----------------------MARF------- 253

  Fly   335 SWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIH-------HFCEAHGHELTVDHTNGLVELF 392
             ||:....:|..|:.....|.....|..:..:|.|.       .|.:::.....:|....|:|:.
Zfish   254 -WLEYLNGDPRLVMSLLANNHTVQSQETEAARAKIDWTRLLPVAFQKSYKPVFPLDGDPKLLEML 317

  Fly   393 THGF--VHAMDRLIQSRLTYGQAPTYLYRFDFD--SPDFNFYRIRFMGKEQRGV 442
            . |.  |.|...|.:|.:.....|.|:...:.|  ..|...|..|.   :|.||
Zfish   318 P-GLLDVRAAPLLAESEVLKAVPPAYIMTCEHDVLRDDGLMYATRL---QQAGV 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 87/444 (20%)
nceh1b.2XP_001335382.3 None

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