Protein Alignment alpha-Est4 and Ces1h

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 553
• Identity: 155/553 - (28%)
• Similarity: 233/553 - (42%)
• Gaps: 115/553 - (20%)

  Fly     5 YNEDAPVVQTTHGKVRG--ILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSK 67
            |....|||.||||||.|  |.|:. :.:....|.|:|:|.||||:|||..|...:||..:::.:.
Mouse    19 YPSSPPVVNTTHGKVLGKYISLEG-FTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATS 82

  Fly    68 PLSKCLQVSTLTKEVEG-------------SEDCLYLNISVKT---LNGDPMPVMVYIHGGAFKG 116
            ....|.|.:.|.:.|..             ||||||||:....   .|.:.:||||:||||....
Mouse    83 YPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVV 147

  Fly   117 GDSSRRAW-GPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAAN 180
            |.:|  |: |......||||.::|.:||...||.|..|....  ||.|..|.:.||.||:.|.||
Mouse   148 GGAS--AYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSR--GNWGHLDQLAALHWIQDNIAN 208

  Fly   181 FNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGF----SMELNRLPQMEYRLAKHLG 241
            |.|||..:||||.|:|..:|.:|:.||.::.||||||..:|.    .:.:.....:..::|...|
Mouse   209 FGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAG 273

  Fly   242 YE-----------GDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSI-ESYSTPNA 294
            .:           ....:.::||.:.|.:.       |....::....|.||.|:: :....|.|
Mouse   274 CKTTTSAVIVHCLRQKTEEELLEIMQKMNL-------FKLDAQENTKKNYPFLPTVLDGVVLPKA 331

  Fly   295 --VLLAEPIDLQRTTWSNRIPIILGANSGE-GMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRC 356
              .:|||..       .|.:|.|:|.|..| |.::...::..|:.:|    ..::|:...||.
Mouse   332 PEAILAEKN-------FNTVPYIVGINKQEFGWTLPMIMEFPPTDVK----LDKKVISLFLRK-- 383

  Fly   357 DPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQ--------- 412
                       |.:.|      .:..|.....:|.::.|    .|..||:|:...|
Mouse   384 -----------LAYFF------NIPEDGIPVAIEKYSKG----TDDPIQNRVWLLQLIGDVMFGI 427

  Fly   413 -------------APTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSR 464
                         ||||:|.|. ..|.|:   .....|...| .|.||:..:|..| ..:...|.
Mouse   428 PSVIVSRGHRDAGAPTYMYEFQ-SRPSFS---SELKPKTVTG-DHGDEVYSVFGAP-ILREGSSE 486

  Fly   465 PEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDW 497
            .|....:.::..:..||...:||.   :.|..|
Mouse   487 EEINLSKMMMKFWANFARNGNPNG---QGLPHW 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	154/550 (28%)
Ces1h	NP_001357759.1	COesterase	22..546	CDD:395084	154/550 (28%)