Protein Alignment alpha-Est4 and TG

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_003226.4
• Gene: TG / 7038
• HGNCID: 11764
• Length: 2768
• Species: Homo sapiens
• Alignment Length: 43
• Identity: 12/43 - (27%)
• Similarity: 21/43 - (48%)
• Gaps: 7/43 - (16%)

  Fly   315 VHQCFSDFPFIFPSWLAKKFGVQGRTEPSLCMQAAIELSLAFL 357
            |::.||....|:.|||.|       :.|...::..:.|.|:|:
Human    18 VYRFFSRLGQIYQSWLDK-------STPYTAVRWVVTLGLSFV 53

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	12/43 (28%)
TG	NP_003226.4	TY	33..92	CDD:238114	6/28 (21%)
		TY	95..160	CDD:238114
		TY	300..358	CDD:238114
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	521..545
		Thyroglobulin_1	599..658	CDD:459665
		Thyroglobulin_1	662..724	CDD:459665
		TY	730..>776	CDD:469630
		TY	<892..922	CDD:469630
		TY	1004..1073	CDD:238114
		TY	1077..1145	CDD:238114
		TY	1149..1210	CDD:238114
		Type II. /evidence=ECO:0000269|PubMed:8797845	1456..1469
		Ephrin_rec_like	1465..1510	CDD:429604
		Type II. /evidence=ECO:0000269|PubMed:8797845	1470..1486
		Type II. /evidence=ECO:0000269|PubMed:8797845	1487..1503
		TY	1520..1567	CDD:214561
		Type IIIA. /evidence=ECO:0000269|PubMed:8797845	1603..1723
		Type IIIB. /evidence=ECO:0000269|PubMed:8797845	1724..1892
		Type IIIA. /evidence=ECO:0000269|PubMed:8797845	1893..1995
		Type IIIB. /evidence=ECO:0000269|PubMed:8797845	1996..2129
		Type IIIA. /evidence=ECO:0000269|PubMed:8797845	2130..2187
		Cholinesterase-like (ChEL). /evidence=ECO:0000250|UniProtKB:O08710	2188..2768
		COesterase	2197..2718	CDD:395084
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2727..2768