Protein Alignment alpha-Est4 and Ces2el1

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001418901.1
• Gene: Ces2el1 / 688542
• RGDID: 1587637
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 166/586 - (28%)
• Similarity: 254/586 - (43%)
• Gaps: 117/586 - (19%)

  Fly     7 EDAPVVQTTH-GKVRGIL--LKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKP 68
            :.|..::.|| |:|||.|  :|.. |...:.|.|||:|.||:|.|||..|...:||.|:||.:..
  Rat    28 DSASPIRNTHTGQVRGSLVHVKDT-DIDVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDATSH 91

  Fly    69 LSKCLQ------------VSTLTKEVEGSEDCLYLNISVKT--LNGDPMPVMVYIHGGAFKGG-- 117
            .:.|||            :..:...:..|||||||||...|  ..|..:||||:|||||...|
  Rat    92 PAMCLQNDNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEGSNLPVMVWIHGGALTVGMA 156

  Fly   118 ---DSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAA 179
               |.|..|      ..|:||.::|.:|||.|||.|..|.  ...||.|..|.:.||||::.|.|
  Rat   157 SMYDGSMLA------ATEDVVVVTIQYRLGVLGFFSTGDE--HARGNWGYLDQVAALRWVQQNIA 213

  Fly   180 NFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSM---ELNRLPQMEYRLAKHL- 240
            :|.|:|.|:||||.|:|..:|...:.||.|:||||.||:.:|..:   .::|..:|.||:..:|
  Rat   214 HFGGNPNRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLPDLISRSSEMVYRIVANLS 278

  Fly   241 GYEGDNVDSQVLEFLLKA-DPALIVSADFFTPLEKRQGHNMPFK--PSIESYSTPNAVLLAEPID 302
            |...  |||:.|...|:. ..|.|:..            |..||  |::    .....|...|.:
  Rat   279 GCAA--VDSETLMQCLRGKSEAEILDI------------NKVFKIIPAV----VDGEFLPKHPQE 325

  Fly   303 LQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRC-----DPGQRR 362
            |..:...:|:|.|:|.|:.|...|...:..:...::|.   ..:.||..|::..     .|
  Rat   326 LLASANFHRVPSIIGINNDEYGWILPMIFDSAQKIEEI---TRKTLPTVLKSTALKMMLPP---- 383

  Fly   363 QLGQALIHHF---------CEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLY 418
            :.|..|:..:         .:|...|:..|            |:..:..|..:......||.|.|
  Rat   384 ECGDLLMEEYMGDTEDPKTLQAQFREMMGD------------FMFVIPALQVAHFQRSHAPVYFY 436

  Fly   419 RFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIF-KLPATFKLDKSRPEFTAIRRLVAMFVQFAA 482
            .|...|..|...:...:..:     |.||:..:| .|....|...:..|....|:::..:..||.
  Rat   437 EFQHRSSFFKDVKPPHVKAD-----HGDEVFLVFGYLVGDIKFPHTEEEELLSRKIMKYWANFAR 496

  Fly   483 TSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEM------PKLKFF-----DRLYEMA 536
            ..:||   ::.|..|..:....:.:.|:|        ||.:      .:|||:     .::.|:.
  Rat   497 HGNPN---SEGLPHWPVMDHDDQYLQLDI--------QPSVGRALKARRLKFWTKTLPQKIQELK 550

  Fly   537 G 537
            |
  Rat   551 G 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	163/570 (29%)
Ces2el1	NP_001418901.1	COesterase	30..538	CDD:395084	163/569 (29%)