Protein Alignment alpha-Est4 and Ces5a

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 533
• Identity: 145/533 - (27%)
• Similarity: 227/533 - (42%)
• Gaps: 105/533 - (19%)

  Fly    12 VQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQ-- 74
            ||.....|.|.|      |....|.|||:|.||||.|||.:|....||..:|:.:...:.|.|
Mouse    44 VQGKQATVLGRL------EPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNL 102

  Fly    75 --------VSTLTKEVEG-SEDCLYLNI--SVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDY 128
                    :..::..:.| |||||||||  .....||..:||||:|.||.|:.|.:|... |...
Mouse   103 EWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSASIFD-GSAL 166

  Fly   129 FMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGH 193
            .:.|:|:.::|.:|||..||.:..:.  ..|||....|.:.||.|:|.|...|.|:|:.:||||:
Mouse   167 AVYEDVLVVTIQYRLGIFGFFTTQNQ--HAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGN 229

  Fly   194 SSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDN-------VDSQV 251
            |:|::::..|:.||.|..||||||:.:|.::    :|.::         ..||       |.:.|
Mouse   230 SAGAISISSLILSPLSADLFHRAIMQSGVAI----IPSLK---------SSDNDLKHDLQVVANV 281

  Fly   252 LEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYS--TPNAVLLAEPIDLQRTTWSNRIPI 314
            .:..:....||:...     .||.....|......:|::  ...:....||::|........:|.
Mouse   282 CDCNVSDSKALLKCL-----REKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIVPS 341

  Fly   315 ILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIH---HFCEAH 376
            |:|.|:.|           ..::...:..||.:|          |........|||   |....|
Mouse   342 IIGVNNQE-----------CGYILPVRDTPEILL----------GSNESTALTLIHTLLHIPTQH 385

  Fly   377 GHELTVDHTNG----------LVELFTHGFVHAMDRLIQSRLTYGQ---APTYLYRFDFDSPDFN 428
            .:.:|.::.:|          |::||...| ..:..|:.:|  |.:   .|.|.|.|......|.
Mouse   386 LYIVTKEYFHGKHSPTDIRDTLLDLFGDVF-FVVPGLVTAR--YHRDSGGPVYFYEFQHRPHCFQ 447

  Fly   429 FYRIRFMGKEQRGVGHVDELGYIFKLP------ATFKLDKSRPEFTAIRRLVAMFVQFAATSDPN 487
            ..|..|:..:     |.||:.::|..|      ..|: :.:..|....|:::..:..||.:.|||
Mouse   448 NSRPAFVKAD-----HTDEIRFVFGGPFLKGDVVMFE-EATEEEKLLSRKMMKYWANFARSGDPN 506

  Fly   488 APLTKSLVDWKPV 500
            .   ..|..| ||
Mouse   507 G---ADLPPW-PV 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	145/533 (27%)
		Aes	<104..>219	CDD:223730	47/114 (41%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	145/533 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840