DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est4 and aadacl4

DIOPT Version :10

Sequence 1:NP_524266.1 Gene:alpha-Est4 / 40906 FlyBaseID:FBgn0015572 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_001166113.1 Gene:aadacl4 / 569798 ZFINID:ZDB-GENE-080919-2 Length:412 Species:Danio rerio


Alignment Length:408 Identity:78/408 - (19%)
Similarity:138/408 - (33%) Gaps:142/408 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 IRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISVK-----TLNGDPMPVMVYIHGGAFKGGDSSR 121
            |..|.:.:...|::..||          :..:.|:     ..:|:....:||.|||.:..|... 
Zfish    78 IMTCKRSVPHGLRIKDLT----------FSTVPVRVYEPTAASGEKKRGLVYFHGGGWMFGCID- 131

  Fly   122 RAWGPDY-------FMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALR-WIRANA 178
                 ||       .:|.|...:|:|:||.         |:...|  |.|.|..:|.| ::...|
Zfish   132 -----DYDEVCQHISLKSNTTVVSVGYRLA---------PEHRYP--AHLDDCEVATRHFLSIAA 180

  Fly   179 ANFNGDPERITIFGHSSGSMTVQLL-----------LASPQSEGLFHRAILLAGFSMELNRLPQM 232
            .:|..||.|:.:.|.|:|:.....|           |.||.::.|.:.|:.:|.|     .||..
Zfish   181 TDFGVDPCRVAVGGDSAGANLAAALCQRLSKTQDGHLPSPCAQVLIYPALQMADF-----HLPSY 240

  Fly   233 EYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLL 297
            :...:..:.:.|..|                     |..|:...|:....:..:|....|     
Zfish   241 QQNHSVPILFRGRTV---------------------FYFLQYLNGNTSVSQQILEGRHVP----- 279

  Fly   298 AEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQC-------------------N 343
            || :.|:...|       |..||           :.|.::|:.:|                   :
Zfish   280 AE-LKLRYKKW-------LDPNS-----------LPPQFIKQARCQQDLSSHDADVYHIVKQGLD 325

  Fly   344 PE-----------RVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHT----NGLVELFT 393
            ||           |::|......|:....|..| .|........|.::|.:|.    :|::..|.
Zfish   326 PEISPLLAEDDVLRLVPPAFVLTCEFDVLRDDG-FLYQKRLRDLGVDVTWEHLPEGFHGVISFFN 389

  Fly   394 HGFV------HAMDRLIQ 405
            .|::      ..:|.:::
Zfish   390 QGWLTFQSSQRGLDSIVR 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est4NP_524266.1 alpha/beta hydrolases 8..529 CDD:473884 78/408 (19%)
aadacl4NP_001166113.1 Abhydrolase_3 117..383 CDD:400284 67/333 (20%)

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