Protein Alignment alpha-Est4 and nlgn3b

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 614
• Identity: 168/614 - (27%)
• Similarity: 248/614 - (40%)
• Gaps: 138/614 - (22%)

  Fly    10 PVVQTTHGKVRGILLKSLYD-----EQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPL 69
            |.|.|..|::||:.:....:     :|:.   |:|||.||:|..||..|.....|.|:|:.::..
Zfish    46 PTVNTALGRLRGMRVAVATEGLGPVDQYL---GVPYAAPPVGEKRFMPPDAPSAWSGVRNATRFP 107

  Fly    70 SKCLQV-------------------STLTKEVEGSEDCLYLNISVKTLNG--------------- 100
            ..|.|.                   :..|...|.||||||:||.|.|.:|
Zfish   108 PVCPQTVRNAVPDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTE 172

  Fly   101 ---------DPMPVMVYIHGGAFKGG-----DSSRRA-WGPDYFMKENVVYISIGHRLGPLGFLS 150
                     ||.|||::||||::..|     |.|..| :|       ||:.|::.:|:|.|||||
Zfish   173 DDGLRDSRDDPRPVMLFIHGGSYMEGTGNIMDGSVLASYG-------NVIVITLNYRVGILGFLS 230

  Fly   151 LNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHR 215
            ..|.  ...||.||.|.|.|||||..|...|.|||.|:|:||...|:..|.||..|..|||||||
Zfish   231 TGDQ--AAKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHR 293

  Fly   216 AILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQ---- 276
            ||:.:|.::.   ...:.|:..|:.....:.|...||:   ..|..|.:....:..|.:::
Zfish   294 AIIQSGSALS---SWSVNYQPVKYTRLLAERVGCNVLD---TQDLVLCMQKRSYRELVEQEIQPA 352

  Fly   277 GHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQ 341
            ..::.|.|.|:....|:     :|..|..........|:||.|.|||   |.||        |..
Zfish   353 RFHVAFGPVIDGDLIPD-----DPEVLMEQGEFLNYDIMLGVNQGEG---FRFV--------EGV 401

  Fly   342 CNPER------VLPWTLRNRCD-----PGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-H 394
            ..||.      ...:|:.:..|     |..:..|.:.:...:.:....:........||.:|| |
Zfish   402 VEPEEGGVSGSDFDFTVSDFVDSLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVAMFTDH 466

  Fly   395 GFVHAMDRLIQSRLTYGQAPTYLYRF--DFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLP-- 455
            .:|............|| :||:.|.|  ...||         |........|.|||.|:|.:|
Zfish   467 QWVEPAVVTADLHARYG-SPTFFYAFYHHCQSP---------MKPPWADSAHGDELPYVFGVPLI 521

  Fly   456 ---ATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPL---TKSL---------VDWKPVTRFG- 504
               ..|..:.||.:......::..:..||.|.|||.|:   ||.:         |.|   .::|
Zfish   522 GPTELFPCNFSRNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVTW---AKYGP 583

  Fly   505 -KRMVLNISEELKFIPQPEMPKLKFFDRL 532
             .::.|:|..:.:........|:.|:..|
Zfish   584 HDQLYLHIGLKPRVRDHYRATKVAFWKHL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	166/609 (27%)
nlgn3b	XP_005165239.1	COesterase	45..609	CDD:395084	166/609 (27%)
		Herpes_BLLF1	<753..>843	CDD:282904