Protein Alignment alpha-Est4 and ces2a

DIOPT Version :10

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 574
• Identity: 147/574 - (25%)
• Similarity: 236/574 - (41%)
• Gaps: 105/574 - (18%)

  Fly     7 EDAPVVQTTHGKVRGILLKS----LYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSK 67
            :..||....||.|||..:|:    ...||:.   |||:|.||:|..|...|..::.|.|||:.::
Zfish    24 DSGPVAVLKHGSVRGQYVKAKGSPAVVEQYL---GIPFAQPPVGPHRLAAPQPVQGWEGIRNATE 85

  Fly    68 PLSKCLQ----VSTLTKEVE-------GSEDCLYLNISV--KTLNGDPMPVMVYIHGGAFKGGDS 119
            ....|||    :..:.|.::       .||||||||:..  :....:.:|||::||||....|
Zfish    86 HPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIWIHGGGLAMG-- 148

  Fly   120 SRRAWGPDYFMK------------ENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALR 172
                 |...|.:            |.||.:.|.:|||.||:.|..|.  ...||.|..|.|.||:
Zfish   149 -----GACMFKELCLYDGTPLAAYEKVVVVVIQYRLGILGYFSTGDQ--HAKGNWGFLDQIAALQ 206

  Fly   173 WIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLA 237
            |::.|...|.|||:.:||.|.|:|.::..||..||.::|||.|||..:|              :|
Zfish   207 WVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSG--------------VA 257

  Fly   238 KHLGY--EGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAV----- 295
            ...||  :..:..:||:..:.:.|   ..|::......:........|.:.:....|.|.
Zfish   258 TVKGYFVKDPSTHAQVIANITECD---FSSSEVLVKCIREMTEEQIIKAAQKKGIFPGAAVDGEF 319

  Fly   296 LLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLK--EFQCNPERVLPWTLRNRCDP 358
            :.|:|.::.::....::||::|..:.|...:...:.:...|:|  :.:...:|:   .|.|.  .
Zfish   320 IKAQPEEILKSKDFQKVPILIGTTNHEFGWMLPQIFLPKEWVKGMDTKAAKDRL---GLLNA--D 379

  Fly   359 GQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFD 423
            |.....|.....:|..|...|   :..:...||....|:......:.|.......|.|:|.|...
Zfish   380 GASGANGIIADEYFKNAKTPE---EIRDAFTELLGDIFMVIPSITVASYHREAGVPVYMYEFQHG 441

  Fly   424 SPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATF------KLDKSRPEFTAIRRLVAMF-VQFA 481
            ....|.:|..|:..:     |.|::|::|  .|.|      .|.....|...:.|.|..: ..|.
Zfish   442 PSTANKFRPSFVKAD-----HADDVGFVF--GACFWDVHVKGLGTLTEEENQLCRTVMKYRANFI 499

  Fly   482 ATSDPN-APLTKSLVDWKPVTRFGKRMVLNI---------SEELKFIPQPEMPK 525
            .|..|| ||     |.|....:..|.:.|.:         .::|.|..: |:||
Zfish   500 RTGSPNPAP-----VPWPVYDQSNKYLNLGLQQTEGQDLKKDKLLFFTE-ELPK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	alpha/beta hydrolases	8..529	CDD:473884	147/573 (26%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	143/564 (25%)