Protein Alignment alpha-Est4 and nlgn3a

DIOPT Version :9

• Sequence 1: NP_524266.1
• Gene: alpha-Est4 / 40906
• FlyBaseID: FBgn0015572
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 645
• Identity: 176/645 - (27%)
• Similarity: 249/645 - (38%)
• Gaps: 194/645 - (30%)

  Fly    10 PVVQTTHGKVRGILLKSLYDEQFYAFD---GIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSK 71
            |.|.|.:||:||..: .|:.|.....|   |:|||.||:|..||..|.....|.||::.:.....
Zfish    69 PTVNTQYGKLRGARV-PLHSEILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPV 132

  Fly    72 CLQ-VSTLTKEV------------------EGSEDCLYLNISVKT-------------------- 97
            |.| :.....|:                  :.:||||||||.|.|
Zfish   133 CPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICR 197

  Fly    98 ---------------LNGD---------PMPVMVYIHGGAFKGG-----DSSRRA-WGPDYFMKE 132
                           .:||         ..|||||||||::..|     |.|..| :|
Zfish   198 KGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG------- 255

  Fly   133 NVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGS 197
            ||:.|::..|:|.|||||..|.  ...||.||.|.|.|||||..|...|.||..|||:||...|:
Zfish   256 NVIVITLNFRVGVLGFLSTGDQ--AAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGA 318

  Fly   198 MTVQLLLASPQSEGLFHRAILLAGFSME---LNRLPQMEYR-LAKHLGYEG-DNVDSQVLEFLLK 257
            ..|.||..|..|||||||||:.:|.::.   :|..|....| ||:.:|... |.:|  :::.|.|
Zfish   319 SCVSLLTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDTLD--MVDCLRK 381

  Fly   258 ADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGE 322
            .....:|..|.     :...:::.|.|.|:....|:     :|..|..........|:||.|.||
Zfish   382 KSARELVEQDI-----QPARYHVAFGPVIDGDVIPD-----DPEILMEQGEFLNYDIMLGVNQGE 436

  Fly   323 GM--------------------SIFSFVKMNPSWLKEFQCNPE--RVLPWTLR-------NRCDP 358
            |:                    |:..||.....:       ||  ..|..|::       :|.:|
Zfish   437 GLRFVENVVDSEDGVSGNDFDFSVSDFVDSLYGY-------PEGKDTLRETIKFMYTDWADRDNP 494

  Fly   359 GQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFT-HGFVHAMDRLIQSRLTYGQAPTYLYRFDF 422
            ..||:.                       ||.||| |.:|............|| :|||.|.|
Zfish   495 ETRRKT-----------------------LVALFTDHQWVEPSVVTADLHARYG-SPTYFYAF-- 533

  Fly   423 DSPDFNFYRIRFMGKEQ-RGVGHVDELGYIFKLPA-----TFKLDKSRPEFTAIRRLVAMFVQFA 481
                  ::..:.:.|.. ....|.||:.|:|.:|.     .|..:.|:.:......::..:..||
Zfish   534 ------YHHCQSLMKPAWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAVVMTYWTNFA 592

  Fly   482 ATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEEL---KFIPQPEMPKLKFFDRLYEMAGV 538
            .|.|||.|:.:.       |:| .....|..||:   |:.||         |:||...|:
Zfish   593 KTGDPNKPVPQD-------TKF-IHTKANRFEEVAWSKYNPQ---------DQLYLHIGL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est4	NP_524266.1	Abhydrolase	7..529	CDD:304388	172/634 (27%)
		Aes	<104..>219	CDD:223730	59/120 (49%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	176/645 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840